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Pediatric Radiology

, Volume 48, Issue 8, pp 1172–1177 | Cite as

Dysplastic megalencephaly phenotype presenting with prenatal high-output cardiac failure

  • Fernanda Del Campos Braojos
  • Carolina V. A. Guimaraes
Case Report

Abstract

Dysplastic megalencephaly, also known as bilateral hemimegalencephaly, is a rare cerebral malformation characterized by bilateral cerebral hemisphere overgrowth and extensive malformation of cortical development. Affected patients present clinically with intractable seizures, severe neurological impairment and global developmental delay. There is a small body of literature reporting megalencephaly’s association with neonatal high-output cardiac failure and a lack of literature describing prenatal findings. We report a case of dysplastic megalencephaly presenting with progressive high-output cardiac failure during fetal life. Prenatal and postnatal imaging findings as well as neonatal course are described. A companion case with similar imaging findings will help illustrate the prenatal imaging characteristics of this association. Knowledge of this potential complication related to dysplastic megalencephaly may help guide parental counseling and obstetric management.

Keywords

Brain Dysplastic megalencephaly Fetus High-output cardiac failure Magnetic resonance imaging 

Notes

Compliance with ethical standards

Conflicts of interest

None

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Fernanda Del Campos Braojos
    • 1
    • 2
  • Carolina V. A. Guimaraes
    • 1
    • 3
  1. 1.Department of RadiologyTexas Children’s HospitalHoustonUSA
  2. 2.Faculdade de Medicina de São José do Rio Preto (FAMERP)Hospital da Criança e Maternidade de São José do Rio PretoSão José do Rio PretoBrazil
  3. 3.Department of Radiology, Lucile Packard Children’s HospitalStanford UniversityStanfordUSA

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