Pediatric Cardiology

, Volume 39, Issue 8, pp 1650–1655 | Cite as

Prenatal Ultrasonic Diagnosis and Prognostic Analysis of Isolated Left Subclavian Artery (ILSCA) and Left Brachiocephalic Trunk (ILBCT) Malformation

  • Yuntao Li
  • Xiaohong Zhang
  • Yani Yan
  • Qiuyan PeiEmail author
Original Article


The purpose of the study was to explore the prognosis, as well as antenatal ultrasonic features of isolated left subclavian artery (ILSCA) and isolated left brachiocephalic trunk (ILBCT) malformations, in order to improve prognosis and provide guidance for prenatal diagnosis. The origin and routing of cephalic and cervical vessels were observed in patients diagnosed with right aortic arch or right arterial duct arch in our hospital from March 2015 to March 2017, and the spectrum features related to ILSCA and ILBCT were analyzed. Fetuses diagnosed as ILSCA, or, and ILBCT were followed up for 3 months after birth. At the same time, a literature review was carried out for ILBCT and ILSCA in Pubmed. In our study, two cases with ILSCA and ILBCT were both diagnosed prenatally. They are not accompanied by other congenital malformations or chromosome abnormalities. No abnormality was found during postnatal follow-up except that left radial pulsation was weakened and blood pressure of the left upper limb decreased in baby with ILSCA. In baby with ILBCT, in addition to these abnormal changes, the left common carotid artery pulse disappearance too. In pubmed, three of 12 ILSCA or ILBCT did not have other congenital malformation or chromosome abnormalities. They were not diagnosed until the age of 3, 10, and 47 because of school exams or atypical symptoms, such as headaches, chest pain. Symptom of ILBCT or ILSCA without other abnormality is silent, and therefore they cannot be diagnosed timely after birth prenatal diagnosis is necessary for they can be treated in time.


Left subclavian artery Left brachiocephalic trunk Isolated Right aortic arch Right arterial duct 



This study was supported by the Capital Project of Fund Development (No. 2011-4022-07), the Zika Special Project of the MOST (Ministry of Science and Technology) Reform and Development Project.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflicts of interest of relationships to disclose.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer  2018
Corrected publication October/2018

Authors and Affiliations

  • Yuntao Li
    • 1
  • Xiaohong Zhang
    • 2
  • Yani Yan
    • 2
  • Qiuyan Pei
    • 2
    Email author
  1. 1.Department of Obstetric UltrasonographyPeking University People’ HospitalBeijingChina
  2. 2.Department of ObstetricPeking University People’ HospitalBeijingChina

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