Determination of the Polychlorinated Biphenyls Distribution in Different Fat Tissues of Cattle by Age and Gender

  • Ozgür Kuzukiran
  • Ayhan FilaziEmail author
  • Sedat Sevin
  • Begüm Yurdakok-Dikmen
  • Yeliz Yikilmaz
  • Ekrem Erdoğan
  • Filiz Şen
  • Fatma Esra Totan
  • Cagan Celik
  • Ozlem Kirmizibayrak


Polychlorinated biphenyls (PCBs), which cause environmental pollution, are found in animal-based fatty foods. Due to their long half-life and lipophilic properties, they can accumulate in the fat tissues of cattle. The study was conducted to compare the PCB levels (PCB28, 52, 101, 118, 138, 153, and 180) in the different fat tissues (muscle, liver, kidney, spinal cord, lung, back fat, perihepatic fat, and perirenal fat) of cattle by age and gender. This information is also useful to evaluate the exposure risks for different bovine edible tissues. Therefore, 15 female and 15 male cattle under 24 months of age and 15 female and 15 male cattle over 24 months of age were used, and 480 samples were analyzed for target PCBs using gas chromatography-mass spectrometry. Of all the samples, two (50.2 µg/kg in perihepatic fat and 51.1 µg/kg in kidney) were found above the maximum residue limit; these samples were taken from the animals in the elderly female group (over 24 months). There were more PCBs in cattle older than 2 years. Muscle, kidney, and perihepatic fat presented higher PCB concentrations than other tissues, and perirenal fat presented lower PCB concentrations than other tissues. PCB101, PCB153, and PCB138 were found to have the highest contribution to the PCB concentration. Thus, it is concluded that perihepatic fat, muscle, or kidney should be sampled, particularly in routine residue monitoring, and specifically analyzed for PCB101, PCB153, and PCB138.



This study was supported by General Directorate of Agricultural Research and Policies Research in the Ministry of Agriculture and Forestry (Project No: TAGEM/HSGYAD/15/A05/P01/83). The authors sincerely thank the Committee of General Directorate of Agricultural Research and Policies.

Compliance with Ethical Standards

Conflict of interest

The authors declare that there is no conflict of interest regarding the publication of this article.

Supplementary material

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Supplementary material 1 (DOCX 18 kb)


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Ozgür Kuzukiran
    • 1
  • Ayhan Filazi
    • 2
    Email author
  • Sedat Sevin
    • 2
  • Begüm Yurdakok-Dikmen
    • 2
  • Yeliz Yikilmaz
    • 3
  • Ekrem Erdoğan
    • 3
  • Filiz Şen
    • 3
  • Fatma Esra Totan
    • 2
  • Cagan Celik
    • 2
  • Ozlem Kirmizibayrak
    • 3
  1. 1.Veterinary Department, Eldivan Vocational School of Health ServicesCankiri Karatekin UniversityCankiriTurkey
  2. 2.Department of Pharmacology and Toxicology, Faculty of Veterinary MedicineAnkara UniversityDiskapi-AnkaraTurkey
  3. 3.Etlik Veterinary Research Control InstituteEtlik, AnkaraTurkey

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