European Journal of Plastic Surgery

, Volume 42, Issue 2, pp 111–118 | Cite as

Morbidity of interventions in previously untreated Dupuytren disease: A systematic review

  • Rachael Leung
  • Robert Capstick
  • Angela Lei
  • David Nour
  • Warren M. Rozen
  • David J. Hunter-SmithEmail author


Treatment morbidity in previously untreated, or primary, Dupuytren disease has limited representation in the literature. Despite the clinical importance of stratifying risk of intervention based on treatment history, most articles addressing management complications pool both primary and recurrent disease. The aim of this systematic review was to quantify interventional morbidity in primary Dupuytren disease only and isolate the complication profiles of established interventions in previously untreated patients. A literature search was conducted using keywords on Medline and bibliographic linkage. Excluded papers did not address primary Dupuytren disease complications or did not include separate, primary-only complication data. Rates of morbidity were calculated from pooled data extracted from the included studies. Thirty-five papers met the criteria for inclusion. The review has quantified that open procedures carry higher complication rates than closed in the context of primary Dupuytren disease treatment. Amongst closed procedures, the only rate of skin split was high. It is noteworthy that this review has identified the limited isolated primary disease complication data available in the literature, which should prompt further targeted research. This systematic review addresses quantification of complication rates following treatment of primary Dupuytren disease and demonstrates that open interventions carry greater morbidity than closed. Whilst this study highlights the need for a future investigation, the complication data presented should nonetheless facilitate informed decision-making for clinicians and patients when considering initial treatments for primary Dupuytren disease.

Level of Evidence: Level IV, therapeutic study.


Dupuytren’s contracture Complication Fasciotomy Collagenase Fasciectomy Dermofasciectomy 


Compliance with ethical standards


The authors received no financial support for the research, authorship and/or publication of this article.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Conflict of interest

Rachael Leung, Robert Capstick, Angela Lei, David Nour, Warren Rozen and David Hunter-Smith declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Rachael Leung
    • 1
    • 2
  • Robert Capstick
    • 1
    • 2
  • Angela Lei
    • 1
    • 2
  • David Nour
    • 1
    • 2
  • Warren M. Rozen
    • 1
    • 2
    • 3
  • David J. Hunter-Smith
    • 1
    • 2
    • 3
    Email author
  1. 1.Department of Plastic, Reconstructive and Hand Surgery, Frankston HospitalPeninsula HealthFrankstonAustralia
  2. 2.Peninsula Clinical SchoolCentral Clinical School at Monash UniversityMelbourneAustralia
  3. 3.Department of Surgery, School of Clinical Sciences at Monash UniversityMonash Medical CentreClaytonAustralia

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