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Clinico-radiological correlation of magnetic resonance imaging findings in patients with idiopathic intracranial hypertension

  • H. Wong
  • K. Sanghera
  • A. Neufeld
  • C. Maxner
  • Jai Jai Shiva ShankarEmail author
Diagnostic Neuroradiology

Abstract

Purpose

Although several studies have reported imaging findings associated with idiopathic intracranial hypertension (IIH), less is known about the correlation between imaging findings and IIH-related symptoms or signs. Our study aimed to determine if clinical features of IIH are correlated with magnetic resonance imaging (MRI) features.

Methods

A retrospective chart review was conducted on consecutive patients presenting at the neuro-ophthalmology department over the last 15 years. All patients diagnosed with IIH were identified and those with available MRI were included in the final analysis. All MRI images were reviewed by a neuroradiologist blinded to the presenting symptoms and signs. Statistical analysis was performed to determine the correlation between the MRI findings with each clinical symptom or sign.

Results

Thirty-one out of 88 patients with the initial diagnosis of IIH had MRI available and were included in the study. Significant correlations were observed between colour vision and amount of perineural fluid around the optic nerve on MRI (r = − 0.382; p = 0.004), disc assessment and intraocular optic nerve protrusion (r = 0.364; p = 0.004), disc assessment and perineural fluid around the optic nerve (r = 0.276; p = 0.033) and disc assessment and venous sinus stenosis (r = 0.351; p = 0.009).

Conclusion

Our study highlights correlations between imaging and clinical findings of IIH. MRI findings in IIH may be useful in ruling out ominous causes of intracranial pressure and risk stratifying ophthalmologic intervention and management of patients with headaches possibly due to IIH.

Keywords

Idiopathic intracranial hypertension Magnetic resonance imaging Retrospective chart review Cerebrospinal fluid 

Notes

Funding Information

No funding was received for this study.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

For this type of study formal consent is not required.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Diagnostic RadiologyDalhousie UniversityHalifaxCanada
  2. 2.Department of OphthalmologyUniversity of British ColumbiaVancouverCanada
  3. 3.Department of Ophthalmology and Visual SciencesDalhousie UniversityHalifaxCanada
  4. 4.Department of Radiology, Rady Faculty of Health SciencesUniversity of ManitobaWinnipegCanada

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