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Neuroradiology

, Volume 61, Issue 8, pp 891–896 | Cite as

Evaluation of multiparametric MRI differentiating sinonasal angiomatous polyp from malignant tumors

  • Xinyan Wang
  • Ying Liu
  • Qinghua Chen
  • Junfang XianEmail author
Head-Neck-ENT Radiology

Abstract

Purpose

Sinonasal angiomatous polyps (SAPs) can be misdiagnosed as malignant tumors due to aggressive clinical behaviors. The purpose of this study was to evaluate the diagnostic accuracy of multiparametric MRI in differentiating SAPs from malignant tumors.

Methods

This retrospective study included 31 patients with pathologically proven SAPs and 36 patients with malignant tumors in maxillary sinus and nasal cavity. All the patients underwent conventional MRI and dynamic contrast-enhanced (DCE) MRI on 3T MR scanners. Diffusion-weighted (DW) MR imaging was performed in 45 patients. All the MR images were retrospectively analyzed independently by two authors.

Results

Significant differences were found in T1 homogeneity, T2 signal intensity ratio, peripheral hypointense rim on T2WI, and soft tissue infiltration between SAP and malignant tumors (P = 0.004, < 0.001, < 0.001, and = 0.001, respectively). SAPs usually show heterogeneous signal intensity on T1WI, peripheral hypointense rim on T2WI, and higher T2 signal intensity ratio. The tumor size of SAP (4.01 ± 1.08 cm) was slightly smaller than that of malignant tumors (4.56 ± 1.12 cm) (P = 0.045). There were significant differences in DCE-MRI parameters including Tpeak, CImax, WR, TIC types, and progressive enhancement (P = 0.009, < 0.001, = 0.001, = 0.001, and < 0.001, respectively) between SAPs and malignant tumors. All the 31 SAPs showed progressive enhancement on DCE-MRI, while none of the malignant tumors showed progressive enhancement (accuracy 100%). The mean ADC of SAP (1.75 ± 0.30 × 10−3 mm2/s) was higher than that of malignant tumors (1.18 ± 0.31 × 10−3 mm2/s) (P < 0.001).

Conclusion

Multiparametric MRI showed high diagnostic performance in differentiating SAPs from malignant tumors. Progressive enhancement on DCE-MRI is the most effective feature of SAP.

Keywords

Diffusion-weighted MRI Dynamic contrast-enhanced MRI Magnetic resonance imaging Neoplasm Paranasal sinus Sinonasal angiomatous polyp 

Notes

Funding

High Level Health Technical Personnel of Bureau of Health in Beijing (2014-2-005); Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support (ZYLX201704); National Key Technology Research and Development Program of the Ministry of Science and Technology of China (2015BAll6H00); “Key Talent Project” of Beijing (2014001); “Set Sail Project” of Fujian Medical University (2017XQ1016).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required.

Informed consent

For this type of retrospective study formal consent is not required.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Xinyan Wang
    • 1
  • Ying Liu
    • 2
    • 3
  • Qinghua Chen
    • 1
  • Junfang Xian
    • 1
    Email author
  1. 1.Department of Radiology, Beijing Tongren HospitalCapital Medical UniversityBeijingChina
  2. 2.Department of RadiologyThe First Affiliated Hospital of Fujian Medical UniversityFuzhouChina
  3. 3.Department of Medical Imaging Technology, College of Medical Technology and EngineeringFujian Medical UniversityFuzhouChina

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