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Neuroradiology

, Volume 61, Issue 5, pp 557–563 | Cite as

Evaluation of 3D fat-navigator based retrospective motion correction in the clinical setting of patients with brain tumors

  • Carl Glessgen
  • Daniel Gallichan
  • Manuela Moor
  • Nicolin Hainc
  • Christian FederauEmail author
Diagnostic Neuroradiology
  • 80 Downloads

Abstract

Purpose

A 3D fat-navigator (3D FatNavs)-based retrospective motion correction is an elegant approach to correct for motion as it requires no additional hardware and can be acquired during existing ‘dead-time’ within common 3D protocols. The purpose of this study was to clinically evaluate 3D FatNavs in the work-up of brain tumors.

Methods

An MRI-based fat-excitation motion navigator incorporated into a standard MPRAGE sequence was acquired in 40 consecutive patients with (or with suspected) brain tumors, pre and post-Gadolinium injection. Each case was categorized into key anatomical landmarks, the temporal lobes, the infra-tentorial region, the basal ganglia, the bifurcations of the middle cerebral artery, and the A2 segment of the anterior cerebral artery. First, the severity of motion in the non-corrected MPRAGE was assessed for each landmark, using a 5-point score from 0 (no artifacts) to 4 (non-diagnostic). Second, the improvement in image quality in each pair and for each landmark was assessed blindly using a 4-point score from 0 (identical) to 3 (strong correction).

Results

The mean image improvement score throughout the datasets was 0.54. Uncorrected cases with light and no artifacts displayed scores of 0.50 and 0.13, respectively, while cases with moderate artifacts, severe artifacts, and non-diagnostic image quality revealed a mean score of 1.17, 2.25, and 1.38, respectively.

Conclusion

Fat-navigator-based retrospective motion correction significantly improved MPRAGE image quality in restless patients during MRI acquisition. There was no loss of image quality in patients with little or no motion, and improvements were consistent in patients who moved more.

Keywords

Motion correction FatNav Brain Tumor Clinic 

Notes

Acknowledgments

CF is supported by the Swiss National Science Foundation.

Compliance with ethical standards

Funding

No funding was received for this study.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in the studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Division of Diagnostic and Interventional Neuroradiology, Department of RadiologyUniversity Hospital BaselBaselSwitzerland
  2. 2.Cardiff University Brain Research Imaging Centre (CUBRIC), School of EngineeringCardiff UniversityCardiffUK
  3. 3.Clinic for NeuroradiologyUniversity Hospital of ZurichZurichSwitzerland
  4. 4.Institute for Biomedical EngineeringETH Zürich and University ZürichZurichSwitzerland

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