European Journal of Clinical Pharmacology

, Volume 75, Issue 1, pp 127–129 | Cite as

Crushing drugs in geriatric units: are cleaning methods and devices appropriate?

  • G. BourdenetEmail author
  • E. Saussereau
  • JP. Goullé
  • M. Guerbet
  • J. Doucet
Letter to the Editor

Swallowing dysfunction, associated notably to neurological diseases, is frequent in old patients [1]. So drugs (pills) are often crushed before oral administration, notably in nursing home and long-care units [2]. However, all drugs cannot be crushed before administration: crushing some drugs (for example drugs with specific galenic for long action) involve pharmacokinetic modifications and can induce bad taste of some active ingredients by altering oral biofilm [3]. Recommendations about crushing drugs are rare and bad known by clinical teams.

We previously conducted a clinical study that revealed that 42% of crushed drugs might not be crushed. This first study lead to the development of recommendations for crushing drugs [4]. Later, we studied the impact of these recommendations on clinical practice. Then we noted that the techniques of cleaning remain various and mortars frequently used for crushing drugs were often worn [5]. However, an insufficient cleaning of devices exposes a...


Author contributions

Bourdenet G. designed the study, performed the research, analyzed the data, and wrote the paper.

Saussereau E. performed the research and contributed to new methods.

Goulle JP. designed the study and analyzed the data.

Guerbet M. designed the study and analyzed the data.

Doucet J. designed the study, analyzed the data and wrote the paper.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • G. Bourdenet
    • 1
    Email author
  • E. Saussereau
    • 2
  • JP. Goullé
    • 3
  • M. Guerbet
    • 3
  • J. Doucet
    • 4
  1. 1.Department of Immunology – CBHAmiens-Picardie University HospitalAmiens Cedex 1France
  2. 2.Department of ToxicologyLe Havre Hospital CenterLe HavreFrance
  3. 3.Department of Toxicology, UNIROUENNormandy UniversityRouenFrance
  4. 4.Service of Polyvalente Internal MedicineRouen University HospitalRouenFrance

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