Analytics 4.0: Online wastewater monitoring by GC and HPLC
We present an automatically and autonomously operating online laboratory equipped with laboratory chromatographs as an example of Analytics 4.0. At BASF’s largest production site in Ludwigshafen, Germany, multiple GC, HPLC, and IC systems are used in a mostly unstaffed laboratory for automated wastewater monitoring. The purpose of the online system is to prevent unwanted discharges of organic compounds into the wastewater treatment plant and thus protection of the river Rhine. By use of different chromatography and sample preparation techniques, a wide spectrum of compounds can be quantitatively assessed. Most analyzers are coupled to mass spectrometers, and all are equipped with robotic autosamplers. Mixed wastewater samples are collected automatically at 20-min intervals and distributed to the instruments. To operate the online system 24/7, sensors, visualization tools, special software packages, remote access tools, and other assistance systems are required. Many of the software features are as yet not commercially available and thus had to be developed and programmed in-house since they are required in an Analytics 4.0 environment.
KeywordsAnalytics 4.0 Online analytics Wastewater Gas chromatography Liquid chromatography Mass spectrometry
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
- 3.BMBF-Internetredaktion. Zukunftsprojekt Industrie 4.0 - BMBF. 2016. https://www.bmbf.de/de/zukunftsprojekt-industrie-4-0-848.html. Accessed 7 Aug 2019.
- 7.Clemons J. Chromatography in process analysis. Encyclopedia of Analytical Chemistry: Application, Theory and Instrumentation. 2016. https://doi.org/10.1002/9780470027318.a2107.pub3.
- 8.Kessler RW, editor. Prozessanalytik. Weinheim: WILEY-VCH Verlag GmbH & Co. KGaA; 2006.Google Scholar
- 11.Rehorek A. Prozess-Flüssigchromatographie. In: Kessler RW, editor. Prozessanalytik. Weinheim: WILEY-VCH Verlag GmbH & Co. KGaA; 2006. p. 462–4.Google Scholar
- 12.DIN 38407-36 (09/2014): Determination of selected active substances of plant protection products and other organic substances in water – Method using high performance liquid chromatography and mass spectrometric detection (HPLC-MS/MS or -HRMS) after direct injection (F 36).Google Scholar
- 13.DIN 38413-8 (09/2000): Determination of nitrilotriacetic acid (NTA), ethylenedinitrilotetraacetic acid (EDTA) and diethylenetrinitrilopentaacetic acid (DTPA) by liquid chromatography (P 8).Google Scholar