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A biocultural approach to psychiatric illnesses

  • Eric C. ShattuckEmail author
Review

Abstract

Rationale

As a species, humans are vulnerable to numerous mental disorders, including depression and schizophrenia. This susceptibility may be due to the evolution of our large, complex brains, or perhaps because these illnesses counterintuitively confer some adaptive advantage. Additionally, cultural and biological factors may contribute to susceptibility and variation in mental illness experience and expression. Taking a holistic perspective could strengthen our understanding of these illnesses in diverse cultural contexts.

Objectives

This paper reviews some of these potential factors and contextualizes mental disorders within a biocultural framework.

Results

There is growing evidence that suggests cultural norms may influence inflammation, neurotransmitters, and neurobiology, as well as the illness experience. Specific examples include variation in schizophrenia delusions between countries, differences in links between inflammation and emotion between the United States and Japan, and differences in brain activity between Caucasian and Asian participants indicating that cultural values may moderate cognitive processes related to social cognition and interoception.

Conclusions

Research agendas that are grounded in an appreciation of biocultural diversity as it relates to psychiatric illness represent key areas for truly interdisciplinary research that can result in culturally sensitive treatments and highlight possible biological variation affecting medical treatment.

Keywords

Biocultural Depression Schizophrenia Culture Neuroinflammation Evolutionary medicine 

Notes

Acknowledgements

I thank David Samson for his kind and helpful comments, as well as the anonymous reviewers who have helped improve this manuscript.

Compliance with ethical standards

Conflict of interest

The author declares that there is no conflict of interest.

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© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Institute for Health Disparities ResearchUniversity of Texas at San AntonioSan AntonioUSA

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