Understanding conflicts of interest
In the era of evidence-based medicine, clinical decisions about diagnosis and treatment should be informed by best current evidence integrated with clinical expertise and patient values, preferences and experiences . However, conflicts of interest (COIs) could have a detrimental effect on the synthesis, interpretation and application of evidence in the field of intensive care medicine and in healthcare in general [2, 3]. These effects can be complex and difficult to characterise; therefore, better understanding is crucial. Indeed, evidence is open for interpretation. For example, the design, execution, or interpretation of randomised clinical trials (RCTs) and systematic reviews can be affected by various types of COIs (e.g., financial COIs). Similarly, recommendations in clinical practice guidelines can be highly influenced by unmanaged COIs [4, 5, 6]. Furthermore, COIs may affect decision making in daily clinical practice and in quality improvement initiatives, e.g....
Compliance with ethical standards
Conflicts of interest
The authors declare that they have no competing interests.
- 6.Schunemann HJ, Al-Ansary LA, Forland F, Kersten S, Komulainen J, Kopp IB, Macbeth F, Phillips SM, Robbins C, van der Wees P, Qaseem A, Guidelines International Network: Principles for Disclosure of Interests and Management of Conflicts in Guidelines (2015) Guidelines International Network: principles for disclosure of interests and management of conflicts in guidelines. Ann Intern Med 163:548–553CrossRefPubMedGoogle Scholar
- 8.Schunemann HJ, Osborne M, Moss J, Manthous C, Wagner G, Sicilian L, Ohar J, McDermott S, Lucas L, Jaeschke R, Ethics ATS, Conflict of Interest C, the Documents D, Implementation C (2009) An official American Thoracic Society Policy statement: managing conflict of interest in professional societies. Am J Respir Crit Care Med 180:564–580CrossRefPubMedGoogle Scholar