Acute right heart decompensation in a multiple trauma patient with chronic pulmonary hypertension
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We report a case of a 35-year-old woman with a history of long-standing idiopathic pulmonary arterial hypertension [PAH, resting mean pulmonary arterial pressure (mPAP) of 75 mmHg], who was involved in a serious motor vehicle accident. Over the previous 12 years, the patient sustained a high quality of life, as she was successfully treated with orally administered endothelin-receptor antagonist bosentan, continuous intravenous prostacyclin (epoprostenol) infusion through an ambulatory pump device, warfarin and diuretic agents [1, 2].
KeywordsPulmonary Arterial Hypertension Bosentan Spontaneous Breathing Epoprostenol Hypoxic Pulmonary Vasoconstriction
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- 2.Galiè N, Hoeper MM, Humbert M, Torbicki A, Vachiery JL, Barbera JA, Beghetti M, Corris P, Gaine S, Gibbs JS, Gomez-Sanchez MA, Jondeau G, Klepetko W, Opitz C, Peacock A, Rubin L, Zellweger M, Simonneau G, ESC Committee for Practice Guidelines (CPG) (2009) Guidelines for the diagnosis and treatment of pulmonary hypertension: the task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Respir J 34:1219–1263CrossRefPubMedGoogle Scholar