To compare the health-related quality of life (HR-QOL) in acute respiratory distress syndrome (ARDS) survivors with that in a matched control group of non-ARDS survivors.
Design and setting
Prospective, matched, parallel cohort study, comparing HR-QOL between intensive care unit (ICU) survivors with ARDS and a control group in a tertiary care hospital.
Between May 1997 and December 2000, all ARDS adult patients of an eight-bed medical/surgical unit of a tertiary care hospital were enrolled and a control group of non-ARDS survivors, matched for severity of disease and for previous health state, was selected. The study included 29 ARDS survivors who answered the EQ-5D questionnaire and had lung function evaluated.
Measurements and results
A follow-up appointment was performed 6 months after ICU discharge consisting of: (a) evaluation of HR-QOL using EQ-5D and (b) lung function tests and measure of diffusing capacity. Among ARDS survivors 41% had normal lung function and 59% mild to moderate lung function impairments. Nearly a one-third of ARDS survivors reported problems in one or more of the five dimensions of the EQ-5D, and 48% reported feeling worse at the interview than 6 month before ICU admission. No significant differences were found in HR-QOL between ARDS survivors and other ICU survivors with similar age and matched for previous health state and severity of disease.
This study suggests that impairments in HR-QOL among ARDS survivors may not be distinguishable from that among other ICU survivors.
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We thank Alexandra Vieira and Luís Filipe Azevedo for their invaluable help in data management and analysis, and Paula Simão and Paula Negrão for their assistance in lung function evaluation.
An editorial regarding this article can be found in the same issue (http://dx.doi.org/10.1007/s00134-003-1855-3)
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Granja, C., Morujão, E. & Costa-Pereira, A. Quality of life in acute respiratory distress syndrome survivors may be no worst than in other ICU survivors. Intensive Care Med 29, 1744–1750 (2003). https://doi.org/10.1007/s00134-003-1808-x
- Acute respiratory distress syndrome
- Quality of life
- Health-related quality of life
- EQ-5D questionnaire
- Lung function recovery