Advertisement

Occurrence and Risk Assessment of Antibiotics in Manure, Soil, Wastewater, Groundwater from Livestock and Poultry Farms in Xuzhou, China

  • Deming Gu
  • Qiyan FengEmail author
  • Changsheng Guo
  • Song Hou
  • Jiapei Lv
  • Yan Zhang
  • Sheng YuanEmail author
  • Xin ZhaoEmail author
Article

Abstract

Antibiotics in manure, soil, wastewater, and groundwater samples from the livestock and poultry farms in Xuzhou City were investigated in the present study. The concentrations of antibiotics in all matrices varied greatly among farms. Total concentrations of fluoroquinolones and macrolides were much higher than those of sulfonamides in manures and soil samples. Total concentrations of antibiotics in wastewater of livestock farms were higher than those of poultry farm. Josamycin (JM) and tilmicosin (TIL) accounted for more than 74% of the nine macrolides in all groundwater samples. Sulfamethizole (SMT), fleroxacin (FLE), cinoxacin (CIN) and JM were the main antibiotics detected in manure and soil samples, while sulfamethoxypyridazine (SMP), sulfameter (SME), SMT, FLE, JM and TIL accounted for a large proportion of antibiotics in surface and groundwater. The risk assessment of target antibiotics revealed that JM in wastewater showed relatively high RQs for aquatic organisms.

Keywords

Antibiotics Environmental matrices Livestock and poultry farms Risk assessment 

Notes

Acknowledgements

This work was funded by the Postgraduate Research and Innovation Project of Jiangsu Province (Grant No. KYLX16_0569) and the Research on Environmental Safety Monitoring, Assessment and Early Warning Technology of Centralized Drinking Water Source (Grant No. 2018002).

References

  1. Bartelt-Hunt S, Snow DD, Damon-Powell T et al (2011) Occurrence of steroid hormones and antibiotics in shallow groundwater impacted by livestock waste control facilities. J Contam Hydrol 123(3):94–103CrossRefGoogle Scholar
  2. Berendsen BJA, Wegh RS, Memelink J et al (2015) The analysis of animal faeces as a tool to monitor antibiotic usage. Talanta 132(132):258–268CrossRefGoogle Scholar
  3. Bouki C, Venieri D, Diamadopoulos E (2013) Detection and fate of antibiotic resistant bacteria in wastewater treatment plants: a review. Ecotoxicol Environ Saf 91(4):1–9CrossRefGoogle Scholar
  4. Bound JP, Voulvoulis N (2004) Pharmaceuticals in the aquatic environment—a comparison of risk assessment strategies. Chemosphere 56(11):1143–1155CrossRefGoogle Scholar
  5. Boxall A, Blackwell P, Cavallo R et al (2002) The sorption and transport of a sulphonamide antibiotic in soil systems. Toxicol Lett 131(1):19–28CrossRefGoogle Scholar
  6. Carvalho IT, Santos L (2016) Antibiotics in the aquatic environments: a review of the European scenario. Environ Int 94:736–757CrossRefGoogle Scholar
  7. Chen YS, Zhang HB, Luo YM et al (2012) Occurrence and assessment of veterinary antibiotics in swine manures: a case study in East China. Sci Bull 57(6):606–614CrossRefGoogle Scholar
  8. Ding H, Wu Y, Zhang W et al (2017) Occurrence, distribution, and risk assessment of antibiotics in the surface water of Poyang Lake, the largest freshwater lake in China. Chemosphere 184:137–147CrossRefGoogle Scholar
  9. Erik G, Sha C, Berg OG et al (2011) Selection of resistant bacteria at very low antibiotic concentrations. PLoS Pathog 7(7):e1002158CrossRefGoogle Scholar
  10. Grujić S, Vasiljević T, Laušević M (2009) Determination of multiple pharmaceutical classes in surface and ground waters by liquid chromatography-ion trap-tandem mass spectrometry. J Chromatogr A 1216(25):4989–5000CrossRefGoogle Scholar
  11. Hans S, Johnson DJ, Wilson CJ et al (2003) Probabilistic hazard assessment of environmentally occurring pharmaceuticals toxicity to fish, daphnids and algae by ECOSAR screening. Toxicol Lett 144(3):383–395CrossRefGoogle Scholar
  12. Hu XG, Zhou QX, Luo Y (2010) Occurrence and source analysis of typical veterinary antibiotics in manure, soil, vegetables and groundwater from organic vegetable bases, northern China. Environ Pollut 158(9):2992–2998CrossRefGoogle Scholar
  13. Jechalke S, Heuer H, Siemens J et al (2014) Fate and effects of veterinary antibiotics in soil. Trends Microbiol 22(9):536–545CrossRefGoogle Scholar
  14. Kim KR, Owens G, Kwon SI et al (2012) Occurrence and environmental fate of veterinary antibiotics in the terrestrial environment. Water Air Soil Pollut 223(9):6213–6214CrossRefGoogle Scholar
  15. Klaus K (2009) Antibiotics in the aquatic environment: a review—part II. Chemosphere 75(4):417–434CrossRefGoogle Scholar
  16. Leung HW, Minh TB, Murphy MB et al (2012) Distribution, fate and risk assessment of antibiotics in sewage treatment plants in Hong Kong, South China. Environ Int 42(1):1–9CrossRefGoogle Scholar
  17. Li N, Zhang X, Wu W et al (2014) Occurrence, seasonal variation and risk assessment of antibiotics in the reservoirs in North China. Chemosphere 111:327–335CrossRefGoogle Scholar
  18. Li C, Chen J, Wang J et al (2015) Occurrence of antibiotics in soils and manures from greenhouse vegetable production bases of Beijing, China and an associated risk assessment. Sci Total Environ 522(1):101–107CrossRefGoogle Scholar
  19. Lin T, Chen YQ, Chen W (2014a) Toxic effect of sulfadiazine on the growth of zebrafish embryos in the water body. J Safety Environ 14(3):324–327Google Scholar
  20. Lin T, Yu S, Chen Y et al (2014b) Integrated biomarker responses in zebrafish exposed to sulfonamides. Environ Toxicol Pharmacol 38(2):444–452CrossRefGoogle Scholar
  21. Nie M, Yan C, Dong W et al (2015) Occurrence, distribution and risk assessment of estrogens in surface water, suspended particulate matter, and sediments of the Yangtze Estuary. Chemosphere 127:109–116CrossRefGoogle Scholar
  22. Pan X, Qiang Z, Ben W et al (2011) Residual veterinary antibiotics in swine manure from concentrated animal feeding operations in Shandong Province. China Chemosphere 84(5):695–700CrossRefGoogle Scholar
  23. Philipp D, Melanie B, Christina S et al (2012) Accumulation of Pharmaceuticals, Enterococcus, and Resistance Genes in Soils Irrigated with Wastewater for Zero to 100 Years in Central Mexico. PLoS ONE 7(12):e45397Google Scholar
  24. Riaz L, Mahmood T, Khalid A et al (2017) Fluoroquinolones (FQs) in the environment: a review on their abundance, sorption and toxicity in soil. Chemosphere 191:704–720CrossRefGoogle Scholar
  25. Rosa MB, Elida A, Encarnación M et al (2014) Survey of the occurrence of pharmaceuticals in Spanish finished drinking waters. Environ Sci Pollut Res Int 21(18):10917–10939CrossRefGoogle Scholar
  26. Strauss C, Harter T, Radke M (2011) Effects of pH and manure on transport of sulfonamide antibiotics in soil. J Environ Qual 40(5):1652–1660CrossRefGoogle Scholar
  27. Sui Q, Cao X, Lu S et al (2015) Occurrence, sources and fate of pharmaceuticals and personal care products in the groundwater: a review. Emerg Contam 1(1):14–24CrossRefGoogle Scholar
  28. Wang N, Noemie N, Hien NN et al (2009) Adverse effects of enrofloxacin when associated with environmental stress in Tra catfish (Pangasianodon hypophthalmus). Chemosphere 77(11):1577–1584CrossRefGoogle Scholar
  29. Wang Z, Du Y, Yang C et al (2017) Occurrence and ecological hazard assessment of selected antibiotics in the surface waters in and around Lake Honghu, China. Sci Total Environ 609:1423–1432CrossRefGoogle Scholar
  30. Wegst-Uhrich SR, Navarro DA, Zimmerman L et al (2014) Assessing antibiotic sorption in soil: a literature review and new case studies on sulfonamides and macrolides. Chem Cent J 8(1):1–12CrossRefGoogle Scholar
  31. Wei R, Ge F, Huang S et al (2011) Occurrence of veterinary antibiotics in animal wastewater and surface water around farms in Jiangsu Province, China. Chemosphere 82(10):1408–1414CrossRefGoogle Scholar
  32. Wei R, He T, Zhang S et al (2019) Occurrence of seventeen veterinary antibiotics and resistant bacterias in manure-fertilized vegetable farm soil in four provinces of China. Chemosphere 215:234–240CrossRefGoogle Scholar
  33. Weihai X, Wen Y, Xiangdong L et al (2013) Antibiotics in riverine runoff of the Pearl River Delta and Pearl River Estuary, China: concentrations, mass loading and ecological risks. Environ Pollut 182(6):402–407Google Scholar
  34. Yang J, He M, Wu T et al (2018) Sulfadiazine oxidation by permanganate: Kinetics, mechanistic investigation and toxicity evaluation. Chem Eng J 349:56–65CrossRefGoogle Scholar
  35. Zhang H, Zhou Y, Huang Y et al (2016) Residues and risks of veterinary antibiotics in protected vegetable soils following application of different manures. Chemosphere 152:229–237CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.School of Environment Science and Spatial InformaticsChina University of Mining and TechnologyXuzhouChina
  2. 2.State Key Laboratory of Environmental Criteria and Risk AssessmentChinese Research Academy of Environmental SciencesBeijingChina
  3. 3.Jiangsu Agri-Animal Husbandry Vocational CollegeTaizhouChina

Personalised recommendations