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Research Progress on Toxic Effects and Water Quality Criteria of Triclosan

  • Xin Zheng
  • Zhenguang YanEmail author
  • Peiyuan Liu
  • Juntao Fan
  • Shuping Wang
  • Pengyuan Wang
  • Tianxu Zhang
Focused Review

Abstract

Triclosan (TCS) is an effective broad-spectrum antimicrobial agent that is widely used in personal care products. It has been detected in different environmental media, and poses high potential ecological risk. In this article, we carried out a literature review of recent studies on the toxic effects of TCS from different aspects at the molecular, cell, tissue, organ, and individual level. TCS can exhibit acute toxicity to aquatic organisms, affect the normal expression and physiological function of enzymes and genes, and produce cytotoxicity. Many studies have demonstrated that TCS exerts significant endocrine-disrupting effects on organisms, interfering the normal physiological functions of the reproductive, thyroid, and nervous systems via related signaling pathways. Moreover, we reported current research on the water quality criteria of TCS and discuss possible future research directions.

Keywords

Triclosan Toxic effect Cytotoxicity Endocrine-disrupting effect Water quality criteria 

Notes

Acknowledgements

This work was financially supported by the Major Science and Technology Program for Water Pollution Control and Treatment (Grant No. 2017ZX07301002-01).

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Xin Zheng
    • 1
  • Zhenguang Yan
    • 1
    Email author
  • Peiyuan Liu
    • 2
  • Juntao Fan
    • 1
  • Shuping Wang
    • 1
  • Pengyuan Wang
    • 1
  • Tianxu Zhang
    • 1
  1. 1.State Key Laboratory of Environmental Criteria and Risk AssessmentChinese Research Academy of Environmental SciencesBeijingPeople’s Republic of China
  2. 2.School of Life SciencesTianjin UniversityTianjinPeople’s Republic of China

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