Extraction and Trace Analysis of Trihalomethanes in Water Samples Using Zein@Fe3O4 Nanocomposite

  • Fatemeh Hajilari
  • Khalil FarhadiEmail author
  • Habibollah Eskandari


This study presents a simple dispersive solid phase extraction (DSPE) technique combined with headspace thermal desorption (HSTD) for extraction and determination of the most significant trihalomethanes (THMs), bromodichloromethane, bromoform, chloroform and dibromochloromethane, in water samples by using Zein@Fe3O4 nanocomposite coupled with gas chromatography/micro electron capture detection (GC–MECD). Various parameters affecting the DSPE-HSTD performance were investigated and optimized. The obtained results revealed that under optimum conditions, LOD and LOQ values were in the range of 0.1–0.36, 0.3–1.08 µg L−1, respectively. The intra-day and inter-day precisions of the method at a concentration of 10 µg L−1 for each analyte (n = 5) were obtained in the range of 5.69–6.70% and 6.12–7.34%, respectively. Finally, the proposed method was successfully applied for extraction and determination of four THMs in drinking water samples.


Trihalomethnes Zein@Fe3O4 nanocomposite Dispersive solid phase extraction Biopolymer Gas chromatography Environmental analysis 

Supplementary material

128_2019_2567_MOESM1_ESM.docx (31 kb)
Supplementary material 1 (DOCX 30 KB)


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Fatemeh Hajilari
    • 1
  • Khalil Farhadi
    • 2
    Email author
  • Habibollah Eskandari
    • 1
  1. 1.Department of ChemistryUniversity of Mohaghegh ArdabiliArdabilIran
  2. 2.Department of Analytical Chemistry, Faculty of ChemistryUrmia UniversityUrmiaIran

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