, Volume 62, Issue 3, pp 370–372 | Cite as

What do we know about the trends in incidence of childhood-onset type 1 diabetes?

  • Jean M. LawrenceEmail author
  • Elizabeth J. Mayer-Davis


Type 1 diabetes requires intensive ongoing management and may lead to complications that affect multiple organ systems. Concern has been raised about the increasing incidence of type 1 diabetes worldwide, given the impact that type 1 diabetes has on quality of life and the long-term cost to healthcare systems and individuals with diabetes and their families.

Trends in incidence of type 1 diabetes

In this issue of Diabetologia, Patterson et al [1] report the most recent analysis of data from the EURODIAB study, which is comprised of 26 centres in 22 European countries [1]. A 3.4% annual increase in type 1 diabetes from 1989 to 2013 among children <14 years of age was reported, with the rate of increase tending to be reduced in some high-risk countries with higher incidence rates.

Previously, the same group published a report that focused on the incidence of type 1 diabetes using EURODIAB registry data from 1989 to 2008 [2]. This earlier report demonstrated non-uniformity...


Childhood Epidemiology Incidence Trends Type 1 diabetes 



Diabetic ketoacidosis


The Environmental Determinants of Diabetes in the Young


Contribution statement

Both authors were responsible for drafting the article and revising it critically for important intellectual content. Both authors approved the version to be published.

Duality of interest

The authors declare that there is no duality of interest associated with this manuscript.


  1. 1.
    Patterson CC, Harjutsalo V, Rosenbauer J et al (2018) Trends and cyclic variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25-year period 1989–2013: a multicentre prospective registration study. Diabetologia.
  2. 2.
    Patterson CC, Gyürüs E, Rosenbauer J et al (2012) Trends in childhood type 1 diabetes incidence in Europe during 1989-2008: evidence of non-uniformity over time in rates of increase. Diabetologia 55(8):2142–2147. CrossRefPubMedGoogle Scholar
  3. 3.
    Mayer-Davis EJ, Lawrence JM, Dabelea D et al (2017) Incidence trends of type 1 and type 2 diabetes among youths, 2002-2012. N Engl J Med 376(15):1419–1429. CrossRefPubMedPubMedCentralGoogle Scholar
  4. 4.
    Fox DA, Islam N, Sutherland J, Reimer K, Amed S (2018) Type 1 diabetes incidence and prevalence trends in a cohort of Canadian children and youth. Pediatr Diabetes 19(3):501–505. CrossRefPubMedGoogle Scholar
  5. 5.
    The DIAMOND Project Group (2006) Incidence and trends of childhood type 1 diabetes worldwide 1990–1999. Diabet Med 23(8):857–866. CrossRefGoogle Scholar
  6. 6.
    Hamman RF, Bell RA, Dabalea D et al (2014) The SEARCH for Diabetes in Youth study: rationale, findings, and future directions. Diabetes Care 37(12):3336–3344.
  7. 7.
    Weng J, Zhou Z, Guo L et al (2018) Incidence of type 1 diabetes in China, 2010-13: population based study. BMJ 360:j5295. CrossRefPubMedPubMedCentralGoogle Scholar
  8. 8.
    Eisenbarth GS (1986) Type I diabetes mellitus. A chronic autoimmune disease. N Engl J Med 314:1360–1368CrossRefGoogle Scholar
  9. 9.
    Atkinson MA, Eisenbarth GS (2001) Type 1 diabetes: new perspectives on disease pathogenesis and treatment. Lancet 358(9277):221–229. CrossRefPubMedGoogle Scholar
  10. 10.
    Redondo MJ, Steck AK, Pugliese A (2018) Genetics of type 1 diabetes. Pediatr Diabetes 19(3):346–353. CrossRefPubMedGoogle Scholar
  11. 11.
    Barrett JC, Clayton DG, Concannon P et al (2009) Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat Genet 41(6):703–707. CrossRefPubMedPubMedCentralGoogle Scholar
  12. 12.
    Rewers M, Hyöty H, Lernmark Å et al (2018) The Environmental Determinants of Diabetes in the Young (TEDDY) study: 2018 update. Curr Diab Rep 18(12):136. CrossRefPubMedGoogle Scholar
  13. 13.
    Cherubini V, Hermann J, Lesson K et al (2018) DKA at onset of paediatric type 1 diabetes across the world: results from a Joint International Project. Pediatr Diabetes 19(Suppl 26):28–29 (Abstract)Google Scholar
  14. 14.
    Elding Larsson H, Vehik K, Bell R et al (2011) Reduced prevalence of diabetic ketoacidosis at diagnosis of type 1 diabetes in young children participating in longitudinal follow-up. Diabetes Care 34(11):2347–2352. CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Research & EvaluationKaiser Permanente Southern CaliforniaPasadenaUSA
  2. 2.Department of NutritionUniversity of North Carolina at Chapel HillChapel HillUSA
  3. 3.Department of MedicineUniversity of North Carolina at Chapel HillChapel HillUSA

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