Skip to main content
Log in

Von Einsteins Quantentheorie zur modernen Lasertherapie

Historie des Lasers in der Dermatologie und ästhetischen Medizin

  • Leitthema
  • Published:
Der Hautarzt Aims and scope Submit manuscript

Zusammenfassung

Der Laser hat die Behandlungsmöglichkeiten und damit das Fachgebiet der Dermatologie und der ästhetischen Medizin entscheidend mit beeinflusst. Auch in anderen medizinischen Bereichen konnte und kann der Laser neue Optionen in Diagnostik und Therapie eröffnen. In der praktischen Entwicklung der Technologie des Lasers haben Dermatologen, allen voran Dr. Leon Goldman, eine entscheidende Rolle gespielt. Vom Prinzip der stimulierten Emission als Fundament des Lasers durch Albert Einstein 1917 bis zur heutigen alltäglichen Anwendung war es ein langer Weg, der im Folgenden aufgezeigt werden soll.

Abstract

Laser technology has considerably expanded therapeutic modalities in dermatology and aesthetic medicine. In addition, lasers have broadened the spectrum of diagnostic and therapeutic options in many other medical fields. Dermatologists, especially Dr. Leon Goldman, played an important role in the evolution and use of medical lasers. There was a long way from the concept of stimulated emission as the fundamental idea of laser technology by Albert Einstein in 1917 to the practical use of the laser today. We review the development of laser technology from the early days through the latest advances.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1.
Abb. 2.
Abb. 3.
Abb. 4.
Abb. 5.

Literatur

  1. Anderson RR, Margolis RJ, Watenabe S et al. (1989) Selevtive photothermolysis of cutaneous pigmentation by Q-switched Nd:YAG laser pulses at 1064, 532 and 355 nm. J Invest Dermatol 93:38–42

    Google Scholar 

  2. Anderson RR, Parrish JA (1981) Microvasculature can be selectively damaged using dye lasers: a basic theory and experimental evidence in human skin. Lasers Surg Med 1:263–276

    Google Scholar 

  3. Anderson RR, Parrish JA (1983) Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Science 220:524–527

    Google Scholar 

  4. Apfelberg DB, Maser MR, Lash H (1979) Argon laser treatment of decorative tattoos. Br J Plast Surg 32:141–144

    Google Scholar 

  5. Apfelberg DB, Bailin P, Rosenberg H (1986) Preliminary investigation of KTP/532 laser light in the treatment of hemangiomas and tattoos. Laser Surg Med 6:38–42

    Google Scholar 

  6. Arndt KA, Noe JM, Northam DBC et al. (1981) Laser therapy: basic concepts and nomenclature. J Am Acad Dermatol 5:649–654

    Google Scholar 

  7. Arndt K (1982) Adenoma sebaceum: successful treatment with argon laser. Plast Reconstr Surg 70:91–93

    Google Scholar 

  8. Asawanonda P, Anderson RR, Chang Y, Taylor CR (2000) 308-nm excimer laser for the treatment of psoriasis. Arch Dermatol 136:619–624

    Google Scholar 

  9. Bahmer FA, Tang E (1984) Der Neodym:YAG-Laser in der dermatologischen Therapie. Z Hautkr 59:1692–1702

    Google Scholar 

  10. Bailin PL, Ratz JL, Levine HL (1980) Removal of tattoos by CO2 laser. J Dermatol Surg Oncol 6:977–1001

    Google Scholar 

  11. Basov NG, Prokhorov AM (1954) 3-level gas oscillator. Zh Eksp Teor Fiz (JETP) 27:431

    Google Scholar 

  12. Bridges WB (1964) Laser oscillation in singly ionized argon in the visible spectrum. Applied Physics Letters 5:39

    Google Scholar 

  13. Dietrickx CC, Grossman MC, Farinelli WA, Anderson RR (1997) Long-pulsed ruby laser hair removal. Laser Surg Med [Suppl 9]:197

  14. Einstein A (1917) Zur Quantentheorie der Strahlung. Physical Z 18:121–128

    Google Scholar 

  15. Finkel B, Eliezri YD, Waldman A, Slatkine M (1997) Pulsed alexandrite laser technology for noninvasive hair removal. J Clin Laser Med Surg 15:225–229

    Google Scholar 

  16. Fitzpatrick RE, Goldman MP, Ruiz-Esparza J (1993) The use of the alexandrite laser (755 nm, 100 nsec) for tattoo pigment removal in an animal model. J Am Acad Dermatol 28:745–750

    Google Scholar 

  17. Fitzpatrick RE, Goldman MP, Satur NM, Tope WD (1996) Pulsed carbon dioxide laser resurfacing of photoaged facial skin. Arch Dermatol 132:395–402

    Google Scholar 

  18. Geusic JE, Marcos HM, Van Uitert LG (1964). Laser oscillations in Nd-doped yttrium aluminium,yttrium gallium and gadolinium garnets. Applied Physics Letters 4:182

    Google Scholar 

  19. Gilchrest BA, Rosen S, Noe JM (1982) Chilling port wine stains improves the response to argon laser therapy. Plast Reconstr Surg 69:278–283

    Google Scholar 

  20. Goldman L (1983) Historical perspecitve: personal reflecions. In: Arndt KA, Noe JM, Rosen S (eds) Cutaneous laser therapy: principles and methods. John Wiley and Sons Ltd, pp 3–9

  21. Goldman L, Blaney DJ, Kindel DJ Jr et al. (1963) Pathology of the effect of the laser beam on the skin. Nature 197:912–914

    Google Scholar 

  22. Goldman L, Blaney DJ, Kindel DJ Jr, Franke EK (1963) Effect of the laser beam on the skin. J Invest Dermatol 40:121–123

    Google Scholar 

  23. Goldman L, Igelman JM, Richfield DF (1964) Impact of the laser on nevi and melanomas. Arch Dematol 90:71–75

    Google Scholar 

  24. Goldman L, Rockwell J, Meyer R et al. (1967) Laser treatment of tattoos: a preliminary survey of three years' clinical experience. JAMA 20:841–844

    Google Scholar 

  25. Goldman L, Wilson R, Hornby P (1965) Radiation from a Q-switched ruby laser: effect of repeated impacts of power output of 10 megawatts on a tattoo of man. J Invest Dermatol 44:69–71

    Google Scholar 

  26. Gordon JP, Zeiger HJ, Townes CH (1955) The MASER-New type of amplifier, frequency standard and spectrometer. Physiol Rev 99:1264–1274

    Google Scholar 

  27. Greenwald J, Rosen S, Anderson RR et al. (1981) Comparative histological studies of the tunable dye (at 577 nm) laser and argon laser: The specific vascular effects of the dye laser. J Invest Dermatol 77:305–310

    Google Scholar 

  28. Grema H, Raulin C, Greve B (2002) "Skin rejuvenation" durch nichtablative Laser- und Lichtsysteme. Hautarzt 53:385–392

    Google Scholar 

  29. Hall RN, Fenner GE, Kingsley JD et al. (1962) Coherent light emission from GaAs junctions. Physical Rev Letters 9:366

    Google Scholar 

  30. Hecht J (1992) Laser pioneers. Academic Press, Boston San Diego New York London Sydney Tokyo Toronto

  31. Hellwig S, Petzoldt D, König K, Raulin C (1998) Aktueller Stand der Lasertherapie in der Dermatologie. Hautarzt 49:690–704

    Google Scholar 

  32. Itzkan I, Drake EH (1997) History of laser medicine. In: Arndt KA, Dover JS, Olbricht SM (eds) Lasers in cutaneous and aesthetic surgery. Lippincott-Raven Publishers, Philadelphia, pp 3–10

  33. Javan A, Bennett WR Jr, Herriott DR (1961) Population inversion and continous optical maser oscillation in a gas discharge containing a He-Ne mixture. Phys Rev 6:106

    Google Scholar 

  34. Jalkh AE, Pflibsen K, Pomerantzeff O et al. (1988) A new solid-state, frequency-doubled neodymium-YAG photocoagulation system. Arch Ophthalmol 106:847–849

    Google Scholar 

  35. Johnson LF, Nassau K (1961) Infrared fluorescence and stimulated emission of Nd+3 in CaWO4. Proceedings IRE 49:1704

    Google Scholar 

  36. Kaufmann R, Hibst R (1989) Pulsed Erb:YAG and 308 nm UV-excimer laser: in vitro and in vivo study of skin-ablative effects. Lasers Surg Med 9:132–140

    Google Scholar 

  37. Landthaler M, Haina D, Waidelich W et al. (1984) Argon laser therapy of verrucous nevi. Plast Reconstr Surg 74:108–113

    Google Scholar 

  38. Loe E, Biltz H, Koort J et al. (1990) Possible advantages of Excimer lasers in dermatology: an in vitro comparison of ArF and XeCl Excimer, Ar+ and Nd:YAG lasers. Z Hautkr 65:556–561

    Google Scholar 

  39. Maiman TH (1960) Stimulated optical radiation in ruby. Nature 187:493–494

    Google Scholar 

  40. McBurney EI (1978) Carbon dioxide laser surgery of dermatologic lesions. South Med J 71:795–797

    Google Scholar 

  41. McClung RJ, Hellwarth RW (1962) Giant optical pulsations from ruby. J Applied Physics 33:828

    Google Scholar 

  42. Patel CK, Mc Farlane RA, Faust WL (1964) Selective excitation through vibrational energy transfer and optical maser action in N2-CO2. Physiol Rev 13:617–619

    Google Scholar 

  43. Peterson OG, Tuccio SA, Snavely BB (1970) CW operation of an organic dye solution laser. Applied Physics Letters 17:245

    Google Scholar 

  44. Raulin C, Greve B (im Druck) Laser und IPL-Technologie in der Dermatologie und Ästhetischen Medizin, 2. Aufl. Schattauer, Stuttgart New York

  45. Raulin C, Greve B, Raulin S (2001) Ethical considerations concerning laser medicine. Lasers Surg Med 28:100–101

    Google Scholar 

  46. Schäfer FP, Schmidt W, Volze J (1966) Organic dye solution laser. Applied Physics Letters 9:306

    Google Scholar 

  47. Schawlow AL, Townes CH (1958) Infrared and optical masers. Phys Rev 112:1940–1949

    Google Scholar 

  48. Scheibner A, Wheeland RG (1989) Argon-pumped tunable dye laser therapy for facial port-wine stain hemangiomas in adults—a new technique using small spot size and minimal power. J Dermatol Surg Oncol 15:277–282

    Google Scholar 

  49. Solomon H, Goldman L, Henderson B et al. (1968) Histopathology of the laser treatment of port wine lesions. J Invest Dermatol 50:141–146

    Google Scholar 

  50. Sorokin PP, Lankard JR (1966) Stimulated emission observed from an organic dye, chloroaluminum phthalocyanine. IBM J Res Develop 10:162

    Google Scholar 

  51. Sorokin PP, Lankard JR (1967) Flashlamp excitation of organic dye lasers-a short communication. IBM J Res Develop 11:148

    Google Scholar 

  52. Strempel H, Klein G (1983) Über einen neuen Ansatz in der Laser-Therapie des Naevus flammeus. Z Hautkr 58:967–974

    Google Scholar 

  53. Taboada J, Mikesell GW Jr, Reed RD (1981) Response of the corneal epithelium to KrF excimer laser pulses. Health Phys 40:677–683

    Google Scholar 

  54. Tan OT, Murray S, Kurban AK (1989) Action spectrum of vascualr specific injury using pulsed irradiation. J Invest Dermatol 92:868–871

    Google Scholar 

  55. Trokel SL, Srinivasan R, Braren B (1983) Excimer laser surgery of the cornea. Am J Ophthalmol 96:710–715

    Google Scholar 

  56. White AD, Rigden JD (1962) Continuous gas maser operation in the visible. Proc IRE 50:1697

    Google Scholar 

  57. Williams RM, Gladstone HB, Moy RL (1999) Hair removal using an 810 nm gallium aluminum arsenide semiconductor diode laser: a preliminary study. Dermatol Surg 25:935–937

    Google Scholar 

  58. Yahr WZ, Strully KJ (1966) Blood vessel anastomosis by laser and other biomedical applications. J Assoc Adv Med Instr 1:28–31

    Google Scholar 

  59. Zweng HC, Flocks M (1967) Retinal laser photocoagulation. Trans Am Acad Ophthalmol Otolaryngol 71:39–45

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to C. Raulin.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Graudenz, K., Raulin, C. Von Einsteins Quantentheorie zur modernen Lasertherapie. Hautarzt 54, 575–582 (2003). https://doi.org/10.1007/s00105-003-0542-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00105-003-0542-1

Schlüsselwörter

Keywords

Navigation