Cerebral Venous Sinus Stenosis may Cause Intracranial Arterial Hypoperfusion

  • Jiayue Ding
  • Jingwei Guan
  • Xunming Ji
  • Ran MengEmail author


Cerebral venous sinus stenosis (CVSS) is always thought of being associated with raised intracranial pressure (ICP) [1]. Persistent high ICP conduces refractory headache, papilledema and even irreversible visual disturbance [1, 2]. In addition, some symptoms not correlated with high ICP, such as tinnitus, sleep disorder and head noise, are likely caused by increased transstenosis pressure gradient (>8 mm Hg) [3]. Revascularization of venous sinuses and outflow correction can decrease the abnormally elevated ICP and the pressure gradient, both of which are further confirmed as the causative role in the symptoms of CVSS [4, 5]. Although the venographic characteristics of CVSS have been fully reported, the cerebral perfusion status that can also contribute to the symptoms is still unknown. This study reports a female with CVSS-induced cerebral arterial perfusion disorder that returned to normal after stenting across the sinus stenoses, in an attempt to explore the impact of...



This study was sponsored by the National Key R&D Program (2017YFC1308401), the National Natural Science Foundation (81371289), and the Project of Beijing Municipal Top Talent for Healthy Work of China (2014-2-015). The authors would like to thank all patients and doctors who participated in this study for their cooperation.

Compliance with ethical guidelines

Conflict of interest

J. Ding, J. Guan, X. Ji and R. Meng declare that they have no competing interests.

Ethical standards

Additional written informed consent was obtained from the patient in this study or the legal representatives for whom identifying information is included in this article.

Supplementary material

62_2019_833_MOESM1_ESM.tif (882 kb)
The SPECT values in a normal control as a reference to the case.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Neurology, Xuanwu HospitalCapital Medical UniversityBeijingChina
  2. 2.Advanced Center of StrokeBeijing Institute for Brain DisordersBeijingChina
  3. 3.Department of China-America Institute of Neuroscience, Xuanwu HospitalCapital Medical UniversityBeijingChina
  4. 4.Department of Neurosurgery, Xuanwu HospitalCapital Medical UniversityBeijingChina

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