, Volume 14, Issue 1, pp 70–80 | Cite as

Pituitary disorders in pregnancy

  • Alexandra ChrisoulidouEmail author
  • Maria Boudina
  • Niki Karavitaki
  • Eleni Bill
  • John Wass


The pituitary gland is significantly affected during gestation in terms of both size and function. Due to this physiologic adaptation, endocrine evaluation and interpretation of imaging is far more complex than in the non-pregnant state. Pituitary disorders are rare in pregnancy, as they are usually associated with gonadal dysfunction, thereby posing difficulties with fertility. This review will focus on pituitary adenomas (prolactinomas, GH-secreting and ACTH-secreting), their diagnostic handicaps and the recommendations for treatment. We will also discuss the two pituitary disorders encountered in pregnancy, Sheehan’s syndrome and lymphocytic hypophysitis.

Key words

Pituitary gland Pregnancy 


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Copyright information

© Hellenic Endocrine Society 2015

Authors and Affiliations

  • Alexandra Chrisoulidou
    • 1
    Email author
  • Maria Boudina
    • 1
  • Niki Karavitaki
    • 3
  • Eleni Bill
    • 2
  • John Wass
    • 3
  1. 1.Unit of Endocrinology, Theagenio HospitalAristotle University of ThessalonikiThessalonikiGreece
  2. 2.1st Department of Obstetrics & GynaecologyAristotle University of ThessalonikiThessalonikiGreece
  3. 3.Department of Endocrinology, Oxford Centre for Diabetes, Endocrinology and MetabolismChurchill HospitalOxfordUK

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