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Bronchial artery chemotherapy for inoperable non-small-cell lung cancer

Abstract

We applied low-dose cisplatin regimen delivered by an interventional method to twenty-one consecutively treated patients with inoperable NSCLC. The regimen consisted of cisplatin SO mg/m2, mitomycin C 10 mg/m2, and 5-Fu 500 mg/m2. All patients had positive response to the treatment. The overall response rate was 76.2% (CR: 23.8%, PR: 52.4%). The median survival was 25.5±3.2 weeks, which was similar to those obtained by other combination chemotherapies, but the toxicity was significantly reduced. The results suggested that bronchial artery chemotherapy would give the patients with advanced NSCLC a satisfactory early results and a higher quality of life. It is advisable to select bronchial artery chemotherapy as a preoperative treatment for advanced NSCLC.

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Author information

Correspondence to Zequan Yang.

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Yang, Z., Yang, Y., Liu, W. et al. Bronchial artery chemotherapy for inoperable non-small-cell lung cancer. Chin J Cancer Res 7, 219–224 (1995). https://doi.org/10.1007/BF03023478

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Key words

  • Interventional
  • Lung cancer
  • Bronchial artery