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During the last few months we have had the opportunity to check the purity of the following anaesthetics: nitrous oxide, cyclopropane, ether, chloroform, trichloroethylene. We have taken advantage of this to review the principal tests used in this regard. Up to now, we have not found any impurities in the samples examined. However, we have on purpose contaminated some of these in order to prove without doubt the results of the principal reactions.

Depending on the individual anaesthetic, peroxides, propylene, carbon mon-oxyde, carbon dioxide, aldehydes, and phosgene are the impurities most likely to be found. It is possible with a few simple tests to detect most impurities. We believe that the frequent practice of these tests would widen the security margin of modern anaesthesiology.


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Correspondence to J. G. Patoine or J. C. Pouliot.

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Patoine, J.G., Pouliot, J.C. CONTRÔLE DE LA PURETÉ DES SUBSTANCES ANESTHÉSIQUES. Can. Anaes. Soc. J. 7, 64–70 (1960). https://doi.org/10.1007/BF03013686

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