Kirklin JW, Barratt-Boyes BG. Cardiac Surgery. 2nd ed. New York, Edinburgh, London, Melbourne: Churchill Livingstone Inc., 1993; 66–7.
Bellinger DC, Jonas RA, Rappaport LA, et al. Developmental and neurologic sataus of children after heart surgery with hypothermic circulatory arrest or lowflow caidiopulmonary bypass. N Engl J Med 1995; 332: 549–55.
Newburger JW, Jonas RA, Wernovsky G, et al. A comparison of the perioperative neurologic effects of hypothermic circulatory arrest versus low-flow cardiopulmonary bypass in infant heart surgery. N Engl J Med 1993; 329: 1057–64.
Norwood WI, Norwood CR, Ingwall JS, Castaneda AR, Fossel ET. Hypothermic circulatory arrest: 31-phosphorus nuclear magnetic resonance of isolated perfused neonatal rat brain. J Thorac Cardiovasc Surg 1979; 78: 823–30.
Chopp M, Knight R, Tidwell CD, Helpern JA, Brown E, Welch KM. The metabolic effects of mild hypothermia on global cerebral ischemia and recirculation in the cat: comparison to normothermia and hypothermia. J Cereb Blood Flow Metab 1989; 9: 141–8.
Stocker F, Hershkowitz N, Bossi E, et al. Cerebral metabolic studies in situ by 31P-nuclear magnetic resonance after hypothermic circulatory arrest. Ped Res 1986; 20: 867–71.
Sutton LN, Clark BJ, Norwood CR, Woodford EJ, Welsh FA. Global cerebral ischemia in piglets under conditions of mild and deep hypothermia. Stroke 1991; 22: 1567–73.
Jonas RA. Experimental studies of hypothermic circulatory arrest and low flow bypass. Cardiol Young 1993; 3: 299–307.
Mezrow CK, Gandsas A, Sadeghi AM, et al Metabolic correlates of neurologic and behavioral injury after prolonged hypothermic circulatory arrest. J Thorac Cardiovasc Surg 1995; 109: 959–75.
Rich TL, Longer GA. Calcium depletion in rabbit myocardium. Calcium paradox protection by hypothermia and cation substitution. Circ Res 1982; 51: 131–41.
Watanabe T, Orita H, Kobayashi M, Washio M. Brain tissue pH, oxygen tension, and carbon dioxide tension in profoundly hypothermic cardiopulmonary bypass. J Thorac Cardiovasc Surg 1989; 97: 396–401.
Swain JA, McDonald TJ Jr, Griffith PK, Balaban RS, Clark RE, Ceckler T. Low flow hypothermic cardiopulmonary bypass protects the brain. J Thorac Cardiovasc Surg 1991; 102: 76–84.
Greeley WJ, Ungerleider RM, Kern FH, Brusino FG, Smith LR, Reves JG. Effects of cardiopulmonary bypass on cerebral blood flow in neonates, infants and children. Circulation 1989; 80: I 209–15.
Greeley WJ, Bushman GA, Kong DL, Oldham HN, Peterson MB. Effects of cardiopulmonary bypass on ecosanoid metabolism during pediatric cardiovascular surgery. J Thorac Cardiovasc Surg 1988; 95: 842–9.
Murkin JM, Farrar JK, Tweed WA, McKenzie FN, Guiraudon G. Cerebral autoregulation and flow/metabolism coupling during cardiopulmonary bypass: the influence of PaCO2. Anesth Analg 1987; 66: 825–32.
Stullken EH Jr, Milde JH, Michenfenlder JD, Tinker JH. The non-linear responses of cerebral metabolism to low concentrations of halothane, enflurane, isoflurane and thiopental. Anesth 1977; 46:28–34.
Scheinberg P, Stead EA. The cerebral blood flow in male subjects as measured by the nitrous technique: normal values for blood flow, oxygen utilization, glucose utilization, and peripheral resistance with observations on the effect of lilting and anxiety. J Clin Invest 1949; 28: 1163–8.
Kety SS, Schmidt CF. The determination of cerebral blood flow in man by the use of nitrous oxide in low concentrations. Am J Physio 1945; 143: 53–60.
Michenfelder JD, Theye RA. Hypothermia: effect of canine brain and whole-body metabolism. Anesthesiology 1968; 29: 1107.
Greeley WJ, Kern FH, Ungerleider RM, et al. The effect of hypothermic cardiopulmonary bypass and total circulatory arrest on cerebral metabolism in neonates, infants and children. J Thorac Cardiovasc Surg 1991; 101: 783–94.
Julia PL, Kofsky ER, Buckberg GD, Young HH, Bugyi HI. Studies of mycardial protection in the immature heart. I. Enhanced tolerance of immature vs adult myocardium to global ischemia with reference to metabolic differences. J Thorac Cardiovasc Surg 1990; 100: 879–8.
Rosenberg AA, Jones MD Jr, Traystman RJ, Simmons MA, Molteni RA. Response of cerebral blood flow to changes in PCO2 in fetal, newborn and adult sheep. Am J Physiol 1982; 242: H862–6.
Kern FH, Jonas RA, Mayer JE Jr, Hanley FL, Casteneda AR, Hickey PR. Temperature monitoring during CPB in infants: does it predict efficient brain cooling? Ann Thorac Surg 1992; 54: 749–54.
Kern FH, Ungerleider RM, Schulman SR, et al. Comparison of two strategies of CPB cooling on jugular venous oxygen saturation. Anesthesiology 1992; 77: A1136.
Mault JR, Ohtake S, Klingensmith ME, Heinle JS, Greeley WJ, Ungerleider RM. Cerebral metabolism and circulatory arrest: effects of duration and strategies for protection. Ann Thorac Surg 1993; 55: 57–63.
Lytle BW, McCarthy PM, Meaney KM, Stewart RW, Cosgrove DM 3rd. Systemic hypothermia and circulatory arrest combined with arterial perfusion of the superior vena cava. Effective intraoperative cerebral protection. J Thorac Cardiovasc Surg 1995; 109: 738–43.
Yoshimura N, Okada M, Ota T, Nohara H. Pharmacologic intervention for ischemic brain edema after retrograde cerebral perfusion. J Thorac Cardiovasc Surg 1995; 109: 1173–81.
Naik SK, Knight A, Elliott MJ A prospective randomized study of a modified technique of ultrafiltration during pediatric open-heart surgery. Circulation 1991; 84(5 suppl): III 422–31.
Naik SK, Knight A, Elliott MJ. A successful modification of ultrafiltration for cardiopulmonary bypass in children. Perfusion 1991; 6: 41–50.
Journois D, Pouard P, Greeley WJ, Mauriat P, Vouhé P, Safran D. Hemofiltration during cardiopulmonary bypass in pediatric cardiac surgery. Effects on hemostasis, cytokines, and complement components. Anesthesiology 1994; 81: 1181–9.
Skaryak LA, Kirshbom PM, DiBernardo LR, et al. Modified ultrafiltration improves cerebral metabolic recovery after circulatory arrest. J Thorac Cardiovasc Surg 1995; 109: 744–51.