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Transmission of lidocaine hydrochloride across the placenta during caesarian section

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Two per cent lidocaine with 1:200,000 epinephrine was used for lumbar epidural analgesia in nineteen caesarian sections. Maternal and foetal blood lidocaine concentrations were obtained. Maternal uptake, placental transmission, and foetal metabolism of lidocaine are discussed.


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Correspondence to Germain L. Houle.

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Fox, G.S., Houle, G.L. Transmission of lidocaine hydrochloride across the placenta during caesarian section. Can. Anaes. Soc. J. 16, 135–143 (1969). https://doi.org/10.1007/BF03005793

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  • Lidocaine
  • Umbilical Vein
  • Mepivacaine
  • Caesarian Section
  • Oleyl Alcohol