Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

New hemostatic agents in proctology

  • 21 Accesses

Conclusions

1. Adequate surgical technique with meticulous hemostasis is the primary requisite to safeguard against post-operative hemorrhage in proctologic surgery.

2. The newer hemostatic agents are described, including topical thrombin, fibrin foam with thrombin, the gelatin sponge with thrombin, and oxidized cellulose.

3. Oxidized cellulose appears to be the agent of choice in proctologic surgery.

This is a preview of subscription content, log in to check access.

References

  1. 1.

    Bailey, Orville T., and Ingraham, Franc D.: Chemical, clinical, and immunological studies on the products of human plasma fractionation. XXI. The use of fibrin foam as a hemostatic agent in neurosurgery: clinical and pathological studies. Jour. Clin. Investig., 23:991–596 (July) 1944.

  2. 2.

    Bailey, Orville T., and Ingraham, Franc D.: Chemical, clinical and immunological studies on the products of human plasma fractionation. XXII. Fibrin films in neurosurgery with special reference to their use in the repair of dural defects and in the prevention of meningocerebral adhesions. Jour. Clin. Investig., 23-597–600 (July) 1944.

  3. 3.

    Bailey, Orville T., Ingraham, Franc D., Swenson, Orvar, Lowrey, John J., and Bering, Edgar A., Jr.: Human fibrin form with thrombin as a hemostatic agent in general surgery. Experimental studies and clinical use. Surgery, 18:347 (Sept.) 1945.

  4. 4.

    Bering, E. A., Jr.: Clinical uses of products made from human fibrinogen and thrombin. Bull. U. S. Army Med. Dept., 78:53–56 (July) 1944

  5. 5.

    Bering, E. A., Jr.: Chemical, clinical, and immunological studies on the products of human plasma fractionation. XX. The development of fibrin foam as a hemostatic agent and for use in conjunction with human thrombin. Jour. Clin. Investig., 23:586 (July) 1944.

  6. 6.

    Frantz, Virginia Kneeland: New absorbable hemostatic agents. Bull. N. Y. Academy of Medicine, 22:102 (February) 1946.

  7. 7.

    Gorostiaga, Diego Taylor, and Lede, Roberto E.: Hemorrhagic syndromes. Medical treatment of hemorrhage. La Prensa Medica Argentina, 32:2113 (October 26) 1945.

  8. 8.

    Ingraham, Franc D., Bailey, Orville T., and Nulsen, Frank E.: Studies on fibrin foam as a hemostatic agent in neurosurgery, with special reference to its comparison with muscle. Journal of Neurosurgery, 1: 171–181 (May) 1944.

  9. 9.

    Ingraham, Franc D., and Bailey, Orville T.: Clinical use of products of human plasma fractionation. III. The use of preducts of fibrinogen and thrombin in surgery.

  10. 10.

    Kudryashov, V. A.: Thrombin, its properties and method of utilization in surgery. Am Rev. Soviet Med., 2:243–246 (February) 1945.

  11. 11.

    Lattes, Raffaele, and Frantz, Virginia Kneeland: Absorbable gauze in bone surgery. Experimental studies suggesting clinical application in reconstruction of joints. Annals of Surgery, 124:28 (July) 1946.

  12. 12.

    Michael, P., and Abbot, W.: The use of human fibrinogen in reconstructive surgery. J.A.M.A., 123:279 (October) 1943.

  13. 13.

    Morrison, P. R., and Singer, M.: Chemical, clinical, and immunological studies on the products of human plasma fractionation XVII. A note on the absorption rates of fibrin films. Jour. Clinc. Investig., 23:573–575 (July) 1944.

  14. 14.

    O’Conor, Vincent J.: Thrombin (topical), as a hemostatic aid in prostatic surgery. Journal of Urology, 53:584 (April) 1945.

  15. 15.

    Tidrick, R. T. Seegers, W. M., and Marner, E. D.: Clinical experience with thrombin as a hemostatic agent. Surgery, 14:191 (August) 1943.

  16. 16.

    Uihlein, Alfred, Clagett, O. T., Osterberg, Arnold E., and Bennett, Warren A.: Absorbable oxidized cellulose with thrombin as a hemostatic agent in surgical procedures. Surg., Gynec. Obstet., 80–470 (May) 1945.

Download references

Author information

Correspondence to Alfred J. Cantor M.D..

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Cantor, A.J. New hemostatic agents in proctology. Jour. D. D. 14, 166 (1947). https://doi.org/10.1007/BF03001307

Download citation

Keywords

  • Thrombin
  • Anal Canal
  • Gelatin Sponge
  • Hemostatic Agent
  • Oxidize Cellulose