A 62-year-old man with a soft, non-tender, movable mass 2.5×2.5-cm in diameter in the volar surface of the right index finger over the proximal phalanx underwent Tc-99m RBC perfusion and blood-pool scintigraphy to evaluate the vascular nature and extent of the mass. Highly increased activity on early and delayed blood-pool images with increased perfusion was demonstrated in the mass. The lesion with high flow rates and large blood pool spaces was considered highly suggestive of one of the various types of peripheral hemangioma. Angiography revealed a vascular neoplasm with tumor vessels. Microscopic examination of the resected tumor revealed vascular leiomyoma containing numerous dilated vascular channels. These scintigraphic abnormalities were regarded as resulting from hypervascularity demonstrated angiographically and blood pooling within the dilated vascular channels demonstrated histologically. It is concluded that Tc-99m RBC perfusion and blood pool scintigraphy may be an important non-invasive approach to demonstrate vascular leiomyoma prior to surgical biopsy or resection.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Hachisuga T, Hashimoto H, Enjoji M. Angioleiomyoma. A clinicopathologic reappraisal of 562 cases.Cancer 1984; 54: 126–130.
Hollerman JJ, Bernstein MA, Froelich JW, Schkudor G. Detection of hemangiomas using whole-body imaging with technetium-99m labeled RBCs.Clin Nucl Med 1986; 11: 716–717.
Levy I, Danziger Y, Mechlis-Frish S, Lubin E, Mimouni M. Technetium-labeled red blood cell imaging to evaluate soft tissue hemangioma of the hand.Pediatr Dermatol 1988; 5: 47–49.
Johnson RA, Sherman FC. Detection of peripheral soft tissue hemangioma with99mTc-labeled red blood cell pool imaging.J Pediatr. Orthon 1992: 2. 183–186.
Bradley M, Stewart I, Metrewell C. Diagnosis of the peripheral cavernous haemangioma: comparison of ultrasound, CT and RBC scintigraphy.Clin Radiol 1991; 44: 34–37.
Inoue Y, Wakita S, Ohtake T, Ohkubo T, Hayashi N, Nishikawa J, et al. Use of whole-body imaging using Tc-99m RBC in patients with soft-tissue vascular lesions.Clin Nucl Med 1996; 21: 958–959.
Fukuda Y, Murata Y, Umehara I, Yamashita T, Ono C, Iwai T. et al. Perfusion and blood pool scintigraphy for diagnosing soft-tissue arteriovenous malformations.Clin Nucl Med 1999; 24: 232–234.
Robinson SC, Kalish RJ. Leiomyoma in the hand. A case report.Clin Orthop 1990; 255: 121–123.
Boyd R, Bhatt B, Mandell G, Saxe A. Leiomyoma of the hand: a case report and review of the literature.J Hand Surg [Am] 1995; 20: 24–26.
Botte MJ, Silver MA. Leiomyoma of a digital artery.Clin Orthop 1990; 260: 259–262.
Uchida M, Kollma T, Hirase Y, Lizuka T. Clinical characteristics of vascular leiomyoma of the upper extremity: report of 11 cases.Br J Plast Surg 1992; 45: 547–549.
Callé SC, Eaton RG, Littler JW. Vascular leiomyomas in the hand.J Hand Surg [Am] 1994; 19: 281–286.
Glowacki KA, Weiss AP. Vascular leiomyoma of the finger causing bone erosion.J Hand Surg [Am] 1995; 20: 1011–1013.
Front D, Israel O, Kleinhaus U, Gdal-On M. Tc-99m-labeled red blood cells in the evaluation of hemangiomas of the skull and orbit: concise communication.J Nucl Med 1982; 23: 1080–1084.
Murata Y, Yamada I, Umehara I, Shibuya H. The use of three-phase scintigraphy for diagnosing hemangiomas of the extremities. A clinical evaluation.Clin Nucl Med 1997; 22: 372–375.
Murata Y, Yamada I, Umehara I, Ishii Y, Okada N. Perfusion and blood-pool scintigraphy in the evaluation of head and neck hemangiomas.J Nucl Med 1997; 38: 882–885.
About this article
Cite this article
Lim, S.T., Kim, M. & Sohn, M. Tc-99m RBC perfusion and blood-pool scintigraphy in the evaluation of vascular leiomyoma of the hand. Ann Nucl Med 16, 293–296 (2002). https://doi.org/10.1007/BF03000110
- vascular leiomyoma
- Tc-99m RBC scintigraphy