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Studies on auto-digestion

VI. The digestion of living tissues in stomach juice (claude bernard’s experiment)

Summary

Legs of frogs anesthetised with ether are digested more rapidly by stomach juice than those of pithed frogs, or of frogs anesthetised with urethane.

Legs of frogs in whom the sciatic nerve is cut are digested more rapidly than innervated legs.

The larger the surface area of the frog’s legs immersed in gastric juice, the sooner will appear the first signs of digestion.

It is concluded that digestion in this experiment is not due merely to a local process, but possibly results from alkali depletion of the blood.

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Author information

Correspondence to M. H. Maskin M.D..

Additional information

From the Gastro-Intestinal Laboratory, Department of Physiology, Nelson Morris Institute, Michael Reese Hospital, and the Department of Physiology of the University of Chicago.

Aided by the Louis L. Cohen Fund.

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Maskin, M.H., Callahan, R. & Necheles, H. Studies on auto-digestion. American Journal of Digestive Diseases and Nutrition 3, 174–177 (1936). https://doi.org/10.1007/BF02999105

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Keywords

  • Gastric Juice
  • Sciatic Nerve
  • Duodenal Ulcer
  • Digestive Medium
  • Abdominal Vein