The American Journal of Digestive Diseases

, Volume 12, Issue 5, pp 157–162 | Cite as

Disturbances in Sugar Metabolism After Subtotal Gastrectomy

  • Charles L. Glaessner


In a series of 14 cases of subtotal gastrectomy, I could show:
  1. 1)

    that even oral intake of 100 grams glucose provoked characteristic attacks of hyperglycemic shock consisting in manifestations of nausea, vomiting, headache, cramps in the abdomen, coma, nystagmus, in a similar way as Beckerman and Lawrence described them.

  2. 2)

    these attacks are probably caused by a sudden rise of blood sugar.

  3. 3)

    new observations during this shock were made: disorders of the vascular system as increase of the pulse rate, decrease of the systolic and especially, the diastolic blood pressure. In a few cases a comatose condition could be observed: disorientation and soft eyeballs. The objection of Schwartz, Rheingold and Necheles could be refuted.

Further studies are planned to solve the following questions in this type of shock:
  1. 1)

    dehydration (determination of the blood volume),

  2. 2)

    a statement of comatose reactions by encephalography,

  3. 3)

    the question of ketone bodies in blood and urine.



Adipose Tissue Hyperglycemia Blood Sugar Blood Sugar Level Fast Blood Sugar 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. E. Baranyi & E. Sperber, Absorption of glucose against a concentration gradient by the small intestine of the rabbit. Scand Arch, of Physiol., 87, 290, 1939.Google Scholar
  2. F. Beckerman, Spontaneous Hypoglycemia after stomach operations, Deut. Med. Wochensch. 59, 683, 1933.CrossRefGoogle Scholar
  3. P. Carnot and M. Chassevant. Cr. soc. biol. 58 -1165-1905.Google Scholar
  4. Cohen, see Shay.Google Scholar
  5. C. F. Cori, Carbohydrate Metabolism. Phys. Rev. 11, 143, 1931.Google Scholar
  6. Delhounge, Arch pract. pathol., 1. 159, 1931.Google Scholar
  7. Diebold, see Lapp.Google Scholar
  8. Fels, see Shay.Google Scholar
  9. Fiessinger and Biran. Contr. soc. biol., 119, 839, 1935.Google Scholar
  10. Gale, see Weddell.Google Scholar
  11. Glaessner, Charles L., Hyperglycemic Shock. Rev. of Gastr. enteral. 7–528, 1940.Google Scholar
  12. Gershon, see Shay.Google Scholar
  13. J. Groen. The absorption of hexoses from the upper part of the small intestine in men. J. clin, invest. 16, 245, 1937.CrossRefGoogle Scholar
  14. C. G. Johnston and Ravden, I. S. Action of glucose on emptying of the stomach. Ann. of surg., 101, 500, 1935.Google Scholar
  15. A. Koranyi. Deut. Arch fuer Clin. Med. 178–353, 1936.Google Scholar
  16. N. Kotschureff, see London.Google Scholar
  17. London and Kotschureff, Mech. of ailment. Hyperglycemia, Zeitschr. fuer experim. Med. 101, 767, 1937.Google Scholar
  18. F. W. Lapp and H. Diebold. Blood sugar curve in its relation to resection of the stomach. D. Arch. f. Clin. Med. 143-5, 1932.Google Scholar
  19. Laszt, see Verzar and Willbrand.Google Scholar
  20. Lawrence. Glycosuria of lay storage type, Brit. Med. J. 1936, I, 526.CrossRefGoogle Scholar
  21. H. E. Magee and E. Reid. The absorption of glucose from the alimentary canal. J. of Phys. 73, 163, 1931.Google Scholar
  22. Necheles, see Schwartz.Google Scholar
  23. Ravden, J. S., Johnston, P. G., Morrison. Absorption of glucose from the intestine, Am. J. Physiol. 194, 700, 1933.Google Scholar
  24. Reid, see Magee.Google Scholar
  25. A. Shay and G. Gershon — Cohen. Exper. studies in gastr. physiol. in men, Surg., gyn, obstetr. 58, 935, 1934.Google Scholar
  26. Shay, Gershon—Cohen—Fels. Glucose tolerance in anacidity, Am. Arch of Dig. Diseases, 5, 4, 1938.Google Scholar
  27. Schwartz, Rheingold—Necheles. Experiments about the relationship between blood sugar and general complaints following subtotal gastric resection. Am. J. of Dig. Dis., 9, 151, 1942.Google Scholar
  28. H. C. Trimble and S. E. Maddoch. The rate of absorption of glucose from the intestine of the dog, J. biol. chem. 107, 133, 1934.Google Scholar
  29. Verzar and Laszt. Absorption of isotonic solutions of glucose from the intestine. Biol. Zeitsch, 276–21, 1935.Google Scholar
  30. D. Willbrand and L. Laszt. Investigations of the causes of the selective absorption of sugar from the intestine. Bioch. Zsch. 258, 398, 1933.Google Scholar
  31. A. G. Weddell and H. E. D. Gale. Changes in blood sugar level associated with surgical operations. Brit. J. of Surg., 22–80, 1934.Google Scholar

Copyright information

© Springer-Verlag 1945

Authors and Affiliations

  • Charles L. Glaessner
    • 1
  1. 1.New York

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