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The application of serotonin and 5-hydroxyindole-3-acetic acid in the diagnosis of apudoma

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Abstract

In our report, the values of whole blood serotonin (5-HT) in 87 apudoma patients (diagnosed by operation and pathology) were summarized. Among them, the levels of urinary 5-hydroxyindole-3-acetic acid (5-HIAA) of 44 patients were also tested. The results showed that both parametres of apudoma patients were higher than those of non-apudoma, post-operative patients of apudoma as well as the normal. The increasing extent of the levels of whole blood 5-HT and urinary 5-HIAA in small intestinal carcinoid was the most obvious one but that of rectum was not. The referable diagnostic values suggested were: 5-HT>130 ng/ml, 5-HIAA>30 mg/ 24 hours.

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Correspondence to Shuhuai Xu.

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Xu, S., Chen, Y., Chen, H. et al. The application of serotonin and 5-hydroxyindole-3-acetic acid in the diagnosis of apudoma. Chin J Cancer Res 2, 8–12 (1990). https://doi.org/10.1007/BF02997555

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Keywords

  • Small Cell Carcinoma
  • Laryngeal Carcinoma
  • Gastrinoma
  • Carcinoid Syndrome
  • Rectum Carcinoid