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The influence of certain commonly used drugs on the rate of gastric emptying in the normal human subject as determined by an intubation technique

(Atropine, Morphine, Benzedrine, Prostigmine, Nitroglycerine, Syntropan, Mecholyl, Ergotamine Tartrate and Sodium Bicarbonate)

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Conclusions

The gastric emptying curve of five normal human subjects as obtained by repeated aspiration, measurement and reinjection of a test solution was essentially unaltered by clinical doses of atropine sulphate, amphetamine sulphate, prostigmine, nitroglycerine, “Syntropan,” acetyl-B-methylcholine chloride, ergotamine tartrate or sodium bicarbonate. Morphine sulphate produced a delayed inhibition of gastric emptying in each of five experiments.

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ReferencesBibliography

  1. 1.

    Abbott, W. O. and Pendergrass, E. P.: Intubation Studies of the Human Small Intestine: V. The Motor Effects of Single Clinical Doses of Morphine Sulphate in Normal Subjects.Am. J. Roent., 35:289–299, March, 1936.

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Correspondence to Jarrett H Folley or W. Osler Abbott.

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Folley, J.H., Abbott, W.O. The influence of certain commonly used drugs on the rate of gastric emptying in the normal human subject as determined by an intubation technique. Jour. D. D. 9, 202–205 (1942). https://doi.org/10.1007/BF02997319

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Keywords

  • Cellulose
  • Gastric Emptying
  • Ergotamine
  • Atropine Sulphate
  • Normal Human Subject