Transitory achlorhydria to histamine may be produced in dogs by exposure of the gastric mucosa to dilute solutions of mercuric or cupric salts; no effect was noted using salts of lead, manganese and zinc in much greater concentration. Quinone has a similar inhibiting action, while hydroquinone and resorcinol have no effect in 100 times as great concentration. Brilliant green and crystal violet stain the gastric mucosa and inhibit acid secretion.
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Mann, F.D., Mann, F.C. An experimental study of some chemical inhibitors of gastric acidity. American Journal of Digestive Diseases 6, 322–325 (1939). https://doi.org/10.1007/BF02996493
- Gastric Mucosa
- Crystal Violet