In the present study 124 cases of head and neck cancers subjected to radiation therapy were studied and the change in oropharyngeal flora with the radiation therapy noted. 50 cases for comparison with no ENT complaints were taken control. The oropharyngeal flora in the control cases was established as the normal flora. Any other floral constituent was considered to be abnormal oropharyngeal flora. It was found that with radiation there was a statistically significant increase in several constituents of normal as well as abnormal oropharyngeal flora. This increase could be the predisposing factor for post radiation infections especially in post operative patients. Oropharyngeal swabs were sent before, during and after radiation therapy for detailed bacterial and mycotic flora smear and culture examinations.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Abu Sbara KA et al. (1993): Radiotherapeutic effect on oropharyngeal flora in patients with head and neck cancer, JLO March Vol. 107, pp.222–227.
Baskies AM, Chretien PB, Baer SB (1982): Radiation therapy, its effects on immune reactivity. Progress in Clinical Cancer 8: 215–226.
Bera SP et al. (1979):Mycotic flora in chronic conditions for the nose and throat. Thesis MS, ENT, KGMC, Lucknow, July 1970.
Blozis GG, Robinson JE (1968):Oral tissue changes caused by radiation therapy. Dent Clin North America Nov.
Freeman BA (1985): Neisseria, the gram negative cocci. In Burrows text book of microbilogy, 22nd Edition Chap 16, WB Saunder’s Company, Tokyo p.429.
Gourie R, Oucharef (1971): Maxillofacial and buccodental complications in treatments with ionizing radiation. Rev Stornatol Chir Maxillofac March 72(2): 192.
Kapoor AK, Tiwari MC, Khan IU, Tandon VK, Tuteja N, Siddiqui JS, Mehrotra RM (1981): Immune dysfunction followed by immunosuppression after Co60 therapy in patients with malignant tumours. Journal of the Indian Medical Association 77: 45–48.
Leikes K (1974): Changes in the oral flora in the intermediate zones and its significance. Fogorv Sz Oct 67 (10): 298- 300.
Martin MV, Al Tikrit U, Bramlay PA (1981): Yeast flora of the mouth and skin during and after irradiation for oral and laryngeal cancer. J Med Microbiol 1981, Nov 14 (4): 457–67.
Pau HW, Sraehler Phol HJ, Exner M (1985): Yeast fungus flora in tumor irradiation of the upper aerodigestive tract. Nov. 33 (11): 485–8.
Rice DH, Gill C (1979): Effect of irradiation upon the bacterial flora in patients with head and neck cancer. Laryngoscope 89: 1839–1841.
About this article
Cite this article
Mehrotra, R., Agarwal, S.P., Shukla, G.K. et al. Effect of radiation on oropharyngeal flora in patients of head and neck cancer. IJO & HNS 49, 344–349 (1997). https://doi.org/10.1007/BF02994648
- Neck Cancer
- Neck Cancer Patient
- Follow Radiation Therapy
- Streptococcus Viridans
- Oropharyngeal Swab