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Measurements of total body calcium by prompt-gamma neutron activation abalysis using a252Cf source

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Abstract

A clinical neutron activation instrument has been developed for in vivo elemental analysis. Utilizing the prompt-capture gamma ray technique, simultaneous total body (TB) measurements of primarily Ca, but also Cl, N, C, and H are routinely performed. This paper describes a technique for the measurement of TBCa (g) that relies on the use of TBCl as an internal standard. The method has been tested with four anthropomorphic phantoms covering a range of body habitus. The mean discrepancy between the measured and known Ca contents was 3.6%. The technique has been applied to two patient groups, and encouraging results were obtained.

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Correspondence to S. J. S. Ryde.

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Ryde, S.J.S., Morgan, W.D., Compston, J. et al. Measurements of total body calcium by prompt-gamma neutron activation abalysis using a252Cf source. Biol Trace Elem Res 26, 429–437 (1990). https://doi.org/10.1007/BF02992698

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Index Entries

  • In vivo neutron activation analysis
  • Ca measurement
  • neutron activation analysis
  • body composition analysis
  • Ca, in vivo measurement of
  • 252Cf
  • prompt gamma ray neutron activation
  • total body calcium