A clinical neutron activation instrument has been developed for in vivo elemental analysis. Utilizing the prompt-capture gamma ray technique, simultaneous total body (TB) measurements of primarily Ca, but also Cl, N, C, and H are routinely performed. This paper describes a technique for the measurement of TBCa (g) that relies on the use of TBCl as an internal standard. The method has been tested with four anthropomorphic phantoms covering a range of body habitus. The mean discrepancy between the measured and known Ca contents was 3.6%. The technique has been applied to two patient groups, and encouraging results were obtained.
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Ryde, S.J.S., Morgan, W.D., Compston, J. et al. Measurements of total body calcium by prompt-gamma neutron activation abalysis using a252Cf source. Biol Trace Elem Res 26, 429–437 (1990). https://doi.org/10.1007/BF02992698
- In vivo neutron activation analysis
- Ca measurement
- neutron activation analysis
- body composition analysis
- Ca, in vivo measurement of
- prompt gamma ray neutron activation
- total body calcium