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A case of ganglioneuroma in which131I-6ß-iodomethyl-19-norcholest-5(10)-en-3ß-ol scintigraphy showed high uptake in the adrenal gland leading to a misdiagnosis

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We experienced a case in which131I-6ßiodomethyl-l9norcholest-5(10)-en-3ß-ol (131I-adosterol) scintigraphy showed high uptake in the right adrenal gland. We diagnosed functional cortical adenoma because of the finding of131I-adosterol scintigraphy. However, no positive findings for the existence of cortical adenoma were obtained in other examinations and we performed right adrenalectomy. Unexpectedly, pathological finding showed the right adrenal gland was occupied with a large ganglioneuroma. This is an instructive case in which131I-adosterol scintigraphy showed abnormal high uptake in the adrenal gland, in spite of the fact that the adrenal gland was occupied by a tumor derived from adrenal medulla.

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Correspondence to Nobuyoshi Fukumitsu or Hirokazu Ashida or Shigeyuki Ogi or Mayuki Uchiyama or Yutaka Mori or Isao Ikemoto or Noriko Sakamoto or Katsuyoshi Tojo or Makio Kawakami.

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Fukumitsu, N., Ashida, H., Ogi, S. et al. A case of ganglioneuroma in which131I-6ß-iodomethyl-19-norcholest-5(10)-en-3ß-ol scintigraphy showed high uptake in the adrenal gland leading to a misdiagnosis. Ann Nucl Med 20, 69 (2006). https://doi.org/10.1007/BF02985594

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Key words

  • 131I-6beta-iodomethyl-19-norcholest-5(10)-en-3beta-ol
  • adrenal gland
  • ganglioneuroma