A reciprocal translocation between chromosome 2 and 3, designated T2, was viable when homozygous in the ROCK strain ofAedes aegypti. It was backcrossed five times with Delhi wild type material. Despite intensive efforts it was not possible to re-isolate it as a homozygote, indicating that a factor in the Delhi background interacted with the translocation and caused recessive lethality. In certain families inbreeding without the production of genetically marked non-translocation homozygotes suggested that a translocation homozygote line had been isolated but, when outcrossed, all the individuals were found to be translocation heterozygotes. It was shown that a balanced lethal system existed which maintained permanent translocation heterozygosity in this line.
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Uppal, D.K., Curtis, C.F. Interference by recessive lethals in the re-isolation of a translocation homozygote inAedes aegypti . J Genet 62, 53–60 (1975). https://doi.org/10.1007/BF02985166
- Translocation Heterozygote
- Translocation Homozygote
- Balance Lethal System