The object of the study was to determine whether or not U.S. normal data for female Vertebral Bone Mineral Density is suitable for use in an Irish population. One hundred and fifty-six healthy Caucasian women of permanent Irish domicile had bone densitometry performed using single energy quantative computed tomography of L2, L3 and L4 vertebrae. We found that comparison of our results to normal American data shows a slight and progressive increase in bone mineral content of postmenopausal American women with age relative to the Irish population. This difference is small and not sufficient to justify development of separate normal values for Irish women. We conclude that this discrepancy may be due to a combination of environmental and racial factors or to the more rigorous exclusion criteria applied in our study.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Cann, E., Genant, H. Precise measurement of vertebral mineral content using computer tomography. Journal of Computer Assisted Tomography 1980: 4, 493–500.
Cummings, S. R., Browner, W. S., Grady, D., Ettinger, B. Should prescription of postmenopausal therapy be based on the results of bone densitometry? Annals of Internai Medicine 1990: Editorial 113, 565–567.
Genant, H. K., Cann, E., Pozzi-Mucelli, R. S., Kanter, A. S. Vertebral mineral determination by Quantative C.T.: Clinical feasability and normative data. Journal of Computer Assisted Tomography 1983: 7, 554–555.
Genant, H. K., Cann, E., Ettinger, Gordan, G. S. Quantative computed tomography of vertebral spongiosa: A sensitive method for detecting early bone loss after oophrectomy. Annals of Internal Medicine 1982: 97, 699–705.
Genant, H., Blocke, J. E., Steiger, P., Glueer, Ettinger, Appropriate use of bone densitometry. Radiology 1989: 170, 817–822.
Melton, L. J. 3rd, Eddy, D. M., Johnston, Jr. Screening for osteoporosis. Annals of Internal Medicine 1990: 112, 516–528.
Hall, M. L., Heavens, J., Cullum, I. D., Eu, P. J. The range of bone density in normal British women. The British Journal of Radiology 1990: 63, 266–269.
Compson, J. E., Evans, W. D., Crawley, E. O., Evans, C. Bone mineral content in normal U.K. subjects. The British Journal of Radiology 1988: 61, 631–636.
Kalender, W. A., Klotz, E., Suess, C. Vertebral bone mineral analysis: An integrated approach with C.T. Radiology 1987: 164, 419–423.
Steiger, P., Block, J. E., Steiger, S., Heuck, A. F., Friedlander, A., Ettinger, B., Harris, S. T., Glueer, Genant, H. K. Spinal bone mineral density measured with quantative Effect of region of interest, vertebral level and technique. Radiology 1990: 175, 537–543.
Genant, H. Steiger, P., Glueer, New developments in bone densitometry. Postgraduate Medicine 1989: April spec p. 18–22, 33–43.
Banks, L. M., Stevenson, J. Modified method of spinal computed tomography for trabecular bone mineral measurements. Journal of Computer Assisted Tomography 1986: 10, 463–467.
Riggs, R. L., Wanner, H. W., Dunn, W. L., Mazess, R., Offord, K. P., Melton, L. J. 3rd. Differential changes in bone mineral density of the appendicular and axial skeleton with aging: Relationship to spinal osteoporosis. Journal of Clinical Investigation 1981: 67, 328–335.
Pacifici, R., Susman, N., Carr, P. L., Birge, S. J., Avioli, L. V. Single and dual energy tomographic analysis of spinal trabecular bone: A comparative study in normal and osteoporotic women. Journal of Clinical Endocrinology and Metabolism 1987: 64, 209–214.
Pacifici, R., Rupich, R., Griffin, M., Chines, A., Susman, N., Avioli, L. V. Dual energy radiography versus quantative computed tomography for the diagnosis of osteoporosis. Journal of Clinical Endocrinology and Metabolism 1990: 70, 705–710.
Reinbold, W. D., Genant, H., Reiser, U. J., Harris, S. T., Ettinger, B. Bone mineral content in early-postmenopausal and postmenopausal osteoporotic women: Comparison of measurement methods. Radiology 1986: 160, 469–478.
Buchanan, J. R., Myers, C, Greer, R. B. 3rd, Lloyd, T., Varano, L. A. Assessment of the risk of vertebral fracture in menopausal women. Journal of Bone and Joint Surgery 1987: 69, 212–218.
About this article
Cite this article
Harbison, J., Daly, L., Murphy, B. et al. Normal bone density in Irish women: is American normative data suitable for use in Ireland?. I.J.M.S. 161, 66 (1992). https://doi.org/10.1007/BF02983715
- Bone Mineral Density
- Bone Mineral Content
- Bone Densitometry
- Irish Population
- Irish Woman