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Characterization of an alkali-extracted peptidoglycan from KoreanGanoderma lucidum

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Abstract

The biologically active peptidoglycan was purified from the alkali fraction of the fruiting bodies ofGanoderma lucidum and the composition of the peptidoglycan was investigated by conventional analyses. The alkali-extracted peptidoglycan showed differences in chemical compositions from the water-extracted. The alkali-extracted peptidoglycan contained 6.9% protein and 75.9% carbohydrates composed mainly of β-glucose, mannose, and α-glucose. The molecular weight range of the peptidoglycan was determined as 2,000 kDa-1 7 kDa. The peptidoglycan is considered to be a hybrid molecule of polysaccharide chains covalently bound as a side chain to the polypeptide core.

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Correspondence to WonTae Jung.

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Cheong, J., Jung, W. & Park, W. Characterization of an alkali-extracted peptidoglycan from KoreanGanoderma lucidum . Arch Pharm Res 22, 515–519 (1999). https://doi.org/10.1007/BF02979162

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Keywords

  • Ganoderma lucidum
  • Fruiting body
  • Alkali extract
  • Peptidoglycan, Characterization