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Metabolites from the fungusCephalosporium sp. AL031

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A new pyrone derivative, 7, 9-dihydroxy-10-methyl-2H, 4aH, 6H, 10bH-pyrano[5,6-c][2]ben-zopyran-2, 6-dione (1), was isolated from a culture broth of a strain of the fungusCephalosporium sp. AL031, together with three known compounds, 3-acetyl-7-hydroxy-5-methoxyl-3H-isobenzofuran-1-one (2), vermopyrone (3), and 5-methylmellein (4). Their structures were elucidated by spectroscopic analysis including MS and 2D-NMR. Compounds2,3, and4 are reported for the first time from fermentation broth of this fungus through the present study.

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Correspondence to Yun-Mei Bi or Xu-Bin Bi or Fang A or Qian-Rong Zhao.

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Bi, Y., Bi, X., A, F. et al. Metabolites from the fungusCephalosporium sp. AL031. Arch Pharm Res 30, 267–269 (2007). https://doi.org/10.1007/BF02977604

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Key words

  • Cephalosporium sp.
  • Pyrone derivative
  • 3-Acetyl-7-hydroxy-5-methoxyl-3H-isobenzofuran-1-one
  • Vermopyrone
  • 5-Methylmellein
  • Fungal metabolites