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Syntheses of (±)-homoepibatidine analogues

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Syntheses of (±)-homoepibatidine analogues (2), which contain the 8-azabicyclo [3.2.1]octane ring system, were achieved by using palladium-catalyzed reductive-coupling reaction from3 and the analgesic activity was tested by Mouse writhing antinociceptive assay

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Correspondence to Yong-Hyun Kim or Chang-Young Oh or Kee-Young Lee or Yiu-Suk Lee or Young-Hoon Jung or Hyun-Ju Park or Won-Hun Ham.

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Kim, Y., Oh, C., Lee, K. et al. Syntheses of (±)-homoepibatidine analogues. Arch Pharm Res 25, 49 (2002). https://doi.org/10.1007/BF02975260

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Key words

  • Alkaloids
  • Homoepibatidine
  • Analgesics
  • Palladium
  • Stereocontrol