Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Apports de l’entéroscopie proximale dans les diarrhées chroniques associées à un déficit immunitaire

Contribution of proximal endoscopy in chronic diarrhea associated with immuno-deficiency

  • 2 Accesses

  • 1 Citations

Résumé

L’apport de l’entéroscopie dans la mise en évidence de l’étiologie des diarrhées chroniques par déficit immunitaire a été précisé par une étude rétrospective portant sur 225 malades.

Un déficit de l’immunité humorale, global ou sélectif, a été constaté chez 8 malades. L’étude indique que l’observation d’une atrophie villositaire et/ou d’une hyperplasie nodulaire lymphoïde constituent des signes d’appels. La découverte grâce à l’entéroscopie d’une lambliase méconnue apporte des arguments identiques. La connaissance de l’existence d’un déficit sérique en IgA ne dispense pas de l’entéroscopie et de la numération des plasmocytes muqueux compte tenu d’une possible absence de concordance entre immunité locale et immunité systémique.

Summary

Contribution of endoscopy in determination of the etiology of chronic diarrhaa due to immunodeficiency has been clarified by a retrospective study composing 225 patients.

A deficiency of humoral immunity, total or selective, has been found in 8 patients. The study shows that observation of a villous atrophy or nodular lymphoid hyperplasia are significant early signs. Thanks to endoscopy, the discovery of an undiagnosed case of giardiasis brings identical arguments. If you are certain of a deficiency in serum IgA, this does not mean that you can do without endoscopy and numeration of mucous plasmocytes, since of a possible absence of concordance between local and systemic immunity.

This is a preview of subscription content, log in to check access.

Références

  1. 1.

    AJDUKIEWICZ A.B., YOUNGS G.R., BOUCHIER I.A.D. — Nodular lymphoid hyperplasia with hypogammaglobulinaemia.Gut., 1972,13, 589–595.

  2. 2.

    AMENT M.E., RUBIN C.E. — Relation of gardiasis to abnormal intestinal structure and function in gastroinntestinal immunodeficiency syndrome.Gastroenterology, 1972,62, 216–226.

  3. 3.

    AMENT M.E., OCHS H.D., DAVID S.D. — Structure and function of the gastrointestinal tract in primary immunodeficiency syndromes: a study of 39 patients.Medicine, 1973,52, 227–248.

  4. 4.

    AMMAN A.J., HONG R. — Selective IgA deficiency: presentation of 30 cases and a review of the literature.Medicine, 1971,50, 223–236.

  5. 5.

    ANDRE C., ANDRE F., FARGIER M.C. — Distribution of IgA1 and IgA2 plasma cells in various normal human tissues and in the jejunum of plasma IgA-deficient patients.Clin. Exp. Immunol., 1978,33, 327–331.

  6. 6.

    ANDRE C. — Les déficits sélectifs de l’immunité digestive existent-ils?Gastroenterol. Clin. Biol., 1982,6, 218–221.

  7. 7.

    BROOM B.C., DE LA CONCHA E.G., WEBSTER A.D.B., LOEWI G., ASHERSON G.L. — Dichotomy between immunoglobulin synthesis by cells in gut and blood of patients with hypogammaglobulinaemia.Lancet, 1975,2, 253–256.

  8. 8.

    CRABBE P.A., HEREMANS J.F. — The distribution of immunoglobulin-containing cells along the human gastrointestinal tract.Gastroenterology, 1966,51, 305–316.

  9. 9.

    CRABBE P.A., HEREMANS J.F. — Lack of gamma-A-globulin in serum of patients with steatorrhea.Gut., 1966,7, 119–127.

  10. 10.

    DELAMARRE J., DUPAS J.L., CHIVRAC D., CAPRON J.P., MESSERSCHMITT J. — Hypogammaglobulinaemia with lymphoid nodular hyperplasia of the small bowell. Endoscopic diagnosis of one case.Endoscopy, 1976,8, 214–216.

  11. 11.

    GILLON J., ANDRE C., DESCOS L., MINAIRE Y. — Small intestinal IgE-cells in human giardiasis.Gut., 1980,21, 916.

  12. 12.

    HERMANS P.E., HUIZENGA K.A., HOFFMAN H.N., BROWN A.L., MARKOWITZ H. — Dysgammaglobulinemia associated with nodular lymphoid hyperplasia of the small intestine.Am. J. Med., 1966,40, 78–89.

  13. 13.

    HUET P.M., MODIGLIANI R., BOGNEL J.C., RAMBAUD J.C., HIRSCH-MARIE H., RAUTUREAU M., HARTMANN L., BERNIER J.J. — Diarrhée et déficit primaire en immunoglobulines de l’adulte.Path. Biol., 1972,20, 661–680.

  14. 14.

    KAHN L.B., NOVIS B.H. — Nodular lymphoid hyperplasia of the small bowel associated with small bowel reticulum cell lymphoma.Cancer, 1974,33, 837–844.

  15. 15.

    KELLER R.J. — Benign nodular lymphoid hyperplasia of the small bowel.J. Mr Sinai Hosp., 1969,36, 430–434.

  16. 16.

    KERSEY J.H., SPECTOR B.D., GOOD R.A. — Primary immunodeficiency disease and cancer: the immunodeficiency cancer registry.Intern. J. Cancer, 1973,12, 333–347.

  17. 17.

    KRAFT S.C. — The intestinal immune response in giardiasis.Gastroenterology, 1979,76, 877–879.

  18. 18.

    LAMERS C.B.H.W., THEO WAGENER D.J., ASSMANN K.J.M., VAN TONGEREN J.H.M. — Jejunal lymphoma in a patient with primary adult-onset hypogammaglobulinemia and nodular lymphoid hyperplasia of the small intestine.Dig. Dis. Sci., 1980,25, 553–557.

  19. 19.

    LEVIN R.H., FELDMAN S.M. — Endoscopic findings of nodular lymphoid hyperplasia with gardiasis.Gastrointestinal Endosc., 1978,24, 203–204.

  20. 20.

    LEVINSON J.D., NASTRO L.J. — Giardiasis with total villous atrophy.Gastroenterology, 1978,74, 271–275.

  21. 21.

    MATUCHANSKY C., GALIAN A., GOLDFAIN D., RAMBAUD J.C., MODIGLIANI R., BERNIER J.J. — Immunocytes et immunoglobulines du tube digestif au cours des déficits immunitaires primitifs de l’adulte. Etude de 26 cas.Gastroenterol. Clin. Biol., 1977,1, 331–343.

  22. 22.

    MATUCHANSKY C., DUPREY F., BRIAUD M., BABIN P., TOUCHARD G., BLOCH P., LENORMAND Y., MORICHAU-BEAUCHANT M. — Hyperplasie nodulaire lymphoïde diffuse de l’intestin grêle, chez l’adulte sans déficit reconnu de l’immunité générale ni digestive.Gastroenterol. Clin. Biol., 1982,6, 239–248.

  23. 23.

    MILANO A.M., LAWRENCE I.R., HOROWITZ L. — Nodular lymphoid hyperplasia of the small intestine and colon with giardiasis. Case with borderline serum IgA levels.Am. J. Dig. Dis., 1971,16, 735–737.

  24. 24.

    MOULINIER B., MARTIN A., BERGER F. — L’entéroscopie proximale — Résultats — Etude critique (485 cas).Acta Endoscopica, 1982,12, 317–326.

  25. 25.

    PENNY R. — Nodular lymphoid hyperplasia of the small intestine associated with hypogammaglobulinemia.Gastroenterology, 1969,56, 982–985.

  26. 26.

    STEVENS F.M., MAC CARTHY C.F. — The endoscopic demonstration of coeliac disease.Endoscopy, 1976,8, 177–180.

  27. 27.

    WEBSTER A.D.B., KENWRIGHT S., BALLARD J., SHINER M., SLAVIN G., LEVI A.J., LOEWI G., ASHERSON G.L. — Nodular lymphoid hyperplasia of the bowel in primary hypogammaglobulinaemia: study of in vivo and in vitro lymphocyte function.Gut., 1977,18, 364–372.

Download references

Author information

Correspondence to L. Descos.

About this article

Cite this article

Descos, L., André, C., André, F. et al. Apports de l’entéroscopie proximale dans les diarrhées chroniques associées à un déficit immunitaire. Acta Endosc 12, 327 (1982). https://doi.org/10.1007/BF02973714

Download citation

Mots-clés

  • diarrhée
  • déficits immunitaires
  • endoscopie
  • entéroscopie
  • giardiase
  • tumeur villeuse gastrique

Key-words

  • diarrhea
  • endoscopy
  • enteroscopy
  • gastric villous tumour
  • giardiasis intestinalis
  • immuno-deficiency