5-Aminolevulinic acid and its derivatives, which are known to affect the early diagnosis and treatment of cancer, have been synthesized. Simple methods for the synthesis of 5-aminolevulinic acid (ALA), a precursor of porphyrins, have been developed in our laboratory for use in studies on the biosynthesis of porphyrins.
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Kang, M., Kim, D., Kim, J.S. et al. Synthesis of 5-aminolevulinic acid (ALA) and itst-butyl ester for the fluorescence detection of early cancer. Arch Pharm Res 28, 1111–1113 (2005). https://doi.org/10.1007/BF02972970
- 5-Aminolevulinic acid
- Fluorescence detection