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Progress in immunopharmacologic study of Yupingfeng powder


Yupingfeng Powder (YPFP,

), a recipe which consists of Radix Astragalus, Rhizoma Atractylodes Alba and Radix Sileris is originally from the book “Experiences of ZHU Danxi” (written by ZHU Danxi, a famous doctor in the Yuan Dynasty). FZ Kong, YH Shen, et al found that YPFP had action on anti-bacterial adhesion. (1,2) It was used in clinical practice to prevent diseases of respiratory tract, such as Wind-Cold, respiratory infection, allergic rhinitis, bronchial asthma. It was recently found that YPFP could affect extensively the immune system, and the related studies were summarized in this article as follows.

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  1. 1.

    Kong Fanzhi, Xu Xihong, Shen Jinmei, et al. Effect of modified Yupingfeng Powder on respiratory bacterial adhesion in model rats of chronic bronchitis. Chinese J of Tuberculosis and Respiratory Diseases, 1990; 13(6): 331–332.

  2. 2.

    Shen Yonghao, Zhang Min, Kong Fanzhi. Antagonist effect of modified Yupingfeng Powder on adhesion of tracheal mucosa surface in rats with chronic bronchitis. CJIM, 1992; 12(11): 677–679.

  3. 3.

    ZHANG Huiling, CHEN Songquan. Effect of Yupingfeng Powder on immune function of children with upper respiratory infection. Pharmacology and Clinics of Chinese Materia Medica, 1995;(4):37–38.

  4. 4.

    ZHANG Huiling, CHEN Songquan. Clinical and experimental study on treatment of repeated upper respiratory infection by Yupingfeng Powder. New J of TCM 1996; (1): 22–23.

  5. 5.

    Wen Yining, Shi Chuandao. Progress on pharmacologic study of Yupingfeng Powder. Chinese Traditional Patent Medicine, 1993; 15(9): 38–39.

  6. 6.

    Zhu Weixing, Yao Jieming. Observation on therapeutic effect of modified Yupingfeng Granule in treating remission stage of chronic bronchitis. Jiangsu J TCM, 1995; 16(7): 45–46.

  7. 7.

    LIAO Shizhong, LU Shegui. Exploration on relationship of Weiqi and immunoglobulin in prevention and treatment of infection susceptibles with Yupingfeng Powder. Liaoning J TCM, 1993; (11): 18–19.

  8. 8.

    ZHOU Ran, WU Yupeng, JIA Lili, et al. Effect of Yupingfeng Powder on humoral immunity of mice. Academic Message of TCM Research, 1990; (34): 6–11.

  9. 9.

    Huang Taikang. Canon of modern researches on Chinese Recipes. 1st edition. Beijing: Publishing House of Sciences and Technology, 1996: 309–312.

  10. 10.

    Tong Kun, Wu Lianzhong. Enhancing effect of modified Yupingfeng Powder on immune function of mice. Chinese Traditional Patent Medicine, 1995; 17(1): 27–28.

  11. 11.

    Li Shuzhen, Zhao Wenli, QU Xun, et al. Regulatory effect of Yupingfeng oral liquid on immune function of immunosuppressed mice. Chinese Traditional Patent Medicine, 1992; 14(3): 26–27.

  12. 12.

    Ou Yongxin, Kuang Jiezhao, Wang Hongqi, et al. Experimental study on theory of Weiqi. J Guangzhou Med College, 1992; 9(3): 135–140.

  13. 13.

    Chen Xin, Ou Yongxin, Chen Jiewen. Preventive effect of Yupingfeng Powder on Wind-Cold factor mediated macrophage immune function inhibition in mice. Practical J Integrated Traditional Chinese and Western Medicine, 1993; 6(9): 548–549.

  14. 14.

    Chen Xin. Improvement on measurement of PM<p releasing H2O2 and its application in immuno-pharmacologic study of Chinese herbal medicine. Guanxi J TCM, 1993; 16(5): 42–43.

  15. 15.

    Zou Liling, Zou Shuisheng, Xiong Wenshu, et al. Effect of Yupingfeng Powder in inhibiting influenza virus and on immune function of organism. J Chinese Materia Medica, 1990; 13(1): 37–40.

  16. 16.

    Chen Xin, Ou Yongxin, Chen Jiewen, et al. Preventive effect of Yupingfeng Powder on artificial circumstance Wind-Cold mediated immunosuppression in mice. Chinese J Experimental and Clinical Immunology, 1993; 5(5): 46–49.

  17. 17.

    Li Shuying, Chen Jiachang, Miao Lijun, et al. Study on effect of Tixu Ganmaoling on immune function of mice. TCM Research, 1991; 4(1): 22–25.

  18. 18.

    Zheng Yanjun, Jing Hongwei, Li Chaoyin, et al. Morphologic observation on aging test with modified Yupingfeng Powder. Chinese J of Gerontology, 1994; 14(4): 237–239.

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Correspondence to Linjiang Hou or Hongtao Xin.

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Hou, L., Xin, H. Progress in immunopharmacologic study of Yupingfeng powder . CJIM 6, 157–160 (2000).

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