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Primary malignant lymphoma of the breast: Mammographic and ultrasonographic findings

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Malignant lymphoma rarely involves the breast. We describe four cases of primary breast lymphoma encountered in our institution from 1979 through 1996, focusing on mammographic and ultrasonographic findings. The lymphomas were demonstrated by mammography as a well-defined mass in one case, an ill-defined mass in two cases and as diffuse increased opacity in one case. No desmoplastic change or calcification was noted. In 3 cases ultrasonography was used, revealing hypoechoic masses with (1 case) or without (2 case) posterior enhancement. During the past two years, 45 of 197 cancers (23%) were demonstrated as a mass without desmoplastic change or calcification by mammography and ultrasonography at our institution. It can be difficult to distinguish malignant lymphoma from more common diseases of the breast, such as carcinoma, by mammography and ultrasonography.

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  1. 1)

    Wiseman C, Liao KT: Primary lymphoma of the breast.Cancer 29:1705–1712, 1972.

  2. 2)

    Manbo NC, Burke JS, Butler JJ: Primary malignant lymphoma of the breast.Cancer 39:2033–2040, 1977.

  3. 3)

    Smith MR, Brustein S, Straus DJ: Localized non-Hodgkin’s lymphoma of the breast.Cancer 59:351–354, 1987.

  4. 4)

    Katsuki S, Karaki Y, Munekata S,et al: A case of malignant lymphoma producing a mass in the breast.Jpn Clin Surg 50:907–914, 1989 (in Japanese).

  5. 5)

    Terasawa T: Primary non-epithelial malignant tumor of the breast.Jpn Cancer Therapy 12:1226–1233, 1983 (in Japanese).

  6. 6)

    Meyer JE, Kopans DB, Long JC: Mammographic appearance of malignant lymphoma of the breast.Radiology 135:623–626, 1980.

  7. 7)

    Paulus DD: Lymphoma of the breast.Radiol Clin North Am 28:833–840, 1990.

  8. 8)

    Assaly T, Palayew MJ, Lisbona A,et al: General case of the day.RadioGraphics 12:602–605, 1992.

  9. 9)

    Liberman L, Giess CS, Dershaw DD,et al: Non-Hodgkin lymphoma of the breast; Imaging characteristics and correlation with histopathologic findings.Radiology 192:157–160, 1994.

  10. 10)

    Tanaka M, Nakamura H, Ooi H: Image diagnosis of malignant lymphoma.Clin Radiol 30:117–119, 1985 (in Japanese with English summary).

  11. 11)

    Sasaki F, Kido C, Suenaga K,et al: Image diagnosis of malignant lymphoma of the breast.Jpn J Med Imaging 11:231–237, 1992 (in Japanese with English summary).

  12. 12)

    Joen HJ, Akagi T, Hoshida Y,et al: Primary non-Hodgkin malignant lymphoma of the breast; An immunohistochemical study of seven patients and literature review of 152 patients with breast lymphoma in Japan.Cancer 70:2451–2459, 1992.

  13. 13)

    Schouten JT, Weese JL, Carbone PP: Lymphoma of the breast.Ann Surg 194:749–753, 1981.

  14. 14)

    Brustein S, Kimmel M, Lieberman P,et al: Malignant lymphoma of the breast; A study of 53 patients.Ann Surg 205:144–150, 1987.

  15. 15)

    El-Ghazawy IM, Singletary E: Surgical management of primary lymphoma of the breast.Ann Surg 214:724–726, 1991.

  16. 16)

    DeBlasio D, McCormick B, Straus D,et al: Definitive irradiation for localized non-localized lymphoma of breast.Int J Radiat Biol Phys 17:843–846, 1989.

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Correspondence to Koichi Mori or Yoshihiro Inoue or Tsunehiro Nishi or Atsushi Fukuuchi or Kenji Ibukuro or Toshitaka Tsukiyama.

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Mori, K., Inoue, Y., Nishi, T. et al. Primary malignant lymphoma of the breast: Mammographic and ultrasonographic findings. Breast Cancer 5, 93–97 (1998).

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Key words

  • Malignant lymphoma
  • Breast neoplasms