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Two cases of choroidal metastasis from breast cancer

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Abstract

We report two cases of choroidal metastasis from breast cancer. The first case was a 41-year-old woman with loss of her right upper visual area in whom right breast cancer accompanied by lung and choroidal metastases were detected simultaneously. She died without having received radiation therapy for the affected eye 6 months after mastectomy and oophorectomy. The second case was a 34-year-old woman in whom choroidal metastasis causing right visual disturbance was diagnosed 3 years after mastectomy for breast cancer. She received radiation therapy following oophorectomy and her visual acuity completely recovered. She died 7 months later.

Radiation therapy improved her quality of life despite her short survival, because her visual acuity was maintained until death. In general, the life span of patients with choroidal metastases is short because of multiple organ metastases, but to obtain a better quality of life, active treatment of the affected eye is necessary.

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Abbreviations

CT:

Computed tomography

CEA:

Carcinoembryonic antigen

MRI:

Magnetic resonance imaging

CAF:

Cyclophosphamide, adriamycin, and 5-fluorouracil

References

  1. 1)

    Kobayashi H, Murai H: A case of choroidal metastasis from breast cancer.Jpn J Breast Cancer 6:403–407, 1991 (in Japanese).

  2. 2)

    Japanese Breast Cancer Society: General Rules for Clinical and Pathological Recording of Breast Cancer, 10th ed, Kanehara Publish, Tokyo, pp 9–10, 1989 (in Japanese).

  3. 3)

    Minoda K, Komatsu M, Cho M,et al: Metastatic cancer to the uvea.Jpn J Cancer Clin 27:1021–1032, 1981 (in Japanese).

  4. 4)

    Yano M, Oda I, Tabuchi S,et al: Metastatic tumors to the choroid.Jpn J Clin Ophthalmol 45:1347–1350, 1991 (in Japanese).

  5. 5)

    Dobrowsky W: Treatment of choroid metastases.Br J Radiol 61:140–142, 1988.

  6. 6)

    Ogata H, Fukuda M, Haneji K,et al: Two cases of metastatic breast cancer to the eye.J Jpn Soc Clin Surg 55:579–584, 1994 (in Japanese).

  7. 7)

    Mewis L: Breast carcinoma metastatic to the choroid.Ophthalmology 89:147–151, 1982.

  8. 8)

    Maor M, Chan RC, Young SE: Radiotherapy of choroidal metastases; Breast cancer as primary site.Cancer 40:2081–2086, 1977.

  9. 9)

    Ochiai Y, Sunagawa M, Hiraoka M: Radiation therapy for metastatic choroidal tumors.Rinsho Ganka 46:369–372, 1992 (in Japanese).

  10. 10)

    Shinozaki J, Tsuchiya M, Takahashi M: Radiation therapy for choroidal metastases.J Jpn Soc Cancer Ther 24(1):32–41, 1989 (in Japanese).

  11. 11)

    Volpe NJ, Albert DM: Metastases to the uvea. In: Principle and Practice of Ophthalmology, Vol 5, WB Saunders, Philadelphia, pp3260–3270, 1994.

  12. 12)

    Tabuchi S, Oda I, Okawa T: Clinical features of radiation therapy.Rinsho Ganka 31(1):133–139, 1977 (in Japanese).

  13. 13)

    Kaneda S, Ohba H, Sakuma M,et al: Treatment of metastatic choroidal tumors with systemic cyclophos-phamide- adriamycin-fluorouracil (CAF).Jpn Rev Clin Ophthalmol 84:743–746, 1990 (in Japanese).

  14. 14)

    Matsushima T, Yabuki K, Ariwa R,et al: A case of metastatic choroidal tumor confirmed by subretinal fluid cytology.Jpn Rev Clin Ophthalmol 85:932–936, 1991 (in Japanese).

  15. 15)

    Mizuno K, Hirano K, Kuryu M,et al: A case report of uveal tumors metastatic from breast cancer.Folia Ophthalmol Jpn 40(10):2242–2248, 1989 (in Japanese).

  16. 16)

    Fujita M, Kawamura H, Kato M,et al: Two cases of metastatic choroidal tumor treated with irradiation.Folia Ophthalmol Jpn 42:2152–2157, 1991 (in Japanese).

  17. 17)

    Doig RG, Jeal PN, Olver IL,et al: Symptomatic choroidal metastases in breast cancer.Aust NZ J Med 22:349–352, 1992.

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Author information

Correspondence to Shingo Inoue or Kaoru Nagahori or Haruki Yamada or Jun Itakura or Yoshiro Matsumoto.

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Inoue, S., Nagahori, K., Yamada, H. et al. Two cases of choroidal metastasis from breast cancer. Breast Cancer 3, 75 (1996). https://doi.org/10.1007/BF02966967

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Key words

  • Breast cancer
  • Choroidal metastasis
  • Quality of life
  • Radiation therapy
  • Multiple organ metastases