Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Les papillomes de I’œsophage

Papillomas of the esophagus

Los papilomas del esofago

  • 1 Accesses

Résumé

Cet article décrit les caractéristiques endoscopiques, cliniques et histo-pathologiques de 33 papillomes œsophagiens diagnostiqués à Lausanne entre 1973 et 1988, en les comparant aux données de la littérature (103 papillomes). Le papillome de l’cesophage est une lésion rare, de faible dimension, le plus souvent unique et asymptomatique, sans rapport avec le reflux gastro-œsophagien. Les potentialités malignes de la lésion sont apparemment nulles, l’évolutivité faible et la récidive inexistante après exérèse complète. Les signes histologiques d’une lésion virale, recherchés par la technique des sondes biotinylées, sont peu fiables et la quantité de virus 31-33-35 décelée dans notre série est faible. En présence d’une lésion de ce type, le rôle essentiel de l’endoscopiste consiste à exclure la forme rare d’un carcinome « précoce » de type papillaire grâce à une coloration vitale et une biopsie-exérèse sélective. L’impact clinique du papillome œsophagien sur la carcinogenèse épidermoïde est nulle en Occident, étant donné la rareté de la lésion.

Summary

This article describes the endoscopic, clinical and histopathological characteristics of 33 esophageal papillomas diagnosed in Lausanne between 1973 and 1988, and compares them to literature data (103 papillomas). Papilloma of the esophagus is a small-sized, rare lesion, most often isolated and asymptomatic, and non-related to gastroesophageal reflux. The lesion’s potential for malignancy is apparently nil. The evolution is low-grade and recurrences never occur following complete excision. Histological signs of viral infection sought by biotin probes are not reliable, and the quantity of virus 31-33-35 detected in our series is small. In presence of lesions of this type, the chief role of the endoscopist consists in excluding the rare form of papillary-type early carcinoma with the use of vital staining and selective bioptic excision. The clinical impact of esophageal papilloma on epidermoid carcinogenesis is nil in the West, given the rarity of the lesion.

Resumen

Este artéculo describe las caracterésticas endoscópicas, clénicas e histopatológicas de 3 papilomas esofagianos diagnosticados en Lausana entre 1973 y 1988, comparándolos con los datos de la literatura (103 papilomas). El papiloma del esófago es una lesión rara, de escasas dimensiones, en la mayor parte de veces es único y asintomático, sin relación con el reflujo gastrœsofagiano. Las potencialidades malignas de la lesión son aparentemente nulas, la evolución limitada y la recidiva inexistente tras exéresis completa. Los signos histológicas de una lesión viral, investigados mediante la técnica de sondas botiniladas, son poco fiables y la cantidad de virus 31-33-35 descubierta en nuestra serie es pequeña. En presencia de una lesión de este tipo, la función esencial del endoscopista consiste en excluir la forma rara de un carcinoma « precoz » de tipo papilar, gracias a una coloración vital y una biopsia-exéresis selectiva. El impacto clénico del papiloma esofagiano sobre la carcinogénesis epidermica es nulo en Occidente, dada la rareza de la lesión.

This is a preview of subscription content, log in to check access.

References

  1. 1.

    ADLER R.H., CARBERRY D.M., ROSS C.A. — Papilloma of the esophagus; association with hiatal hernia.J. Thorac. Cardiovasc. Surg., 1959,37, 625–635.

  2. 2.

    GINSBURG L. — Multiple papillomas of the esophagus: report of a case.Arch. Oto-laryngol., 1931,14, 570–574.

  3. 3.

    HUNT W.M. — Multiple papillomas of the esophagus: case report.Ann. Otol., 1937,46, 752–753.

  4. 4.

    MCKINNEY R. — Papilloma of the lower end of the esophagus in a child.Ann. Otol., 1931,40, 914–921.

  5. 5.

    MOERSCH H.J., HARRINGTON S.W. — Benign tumors of the esophagus.Ann. Otol., 1944,53, 800–817.

  6. 6.

    QUITADAMO M., BENSON J. — Squamous papilloma of the esophagus. A case report and review of the literature.Am. J. Gastroenterol., 1988,83 (2), 194–201.

  7. 7.

    DUBARRY J.J., RICHIR C, BERNARD J.P. et al. — La papillomatose de l’œsophage. Un cas clinique.Arch. Franç. Mal. App. Dig. Paris, 1967,56, 713–720.

  8. 8.

    WEITZNER S., HENTEL W. — Squamous papilloma of the esophagus. Case report and review of the literature.Am. J. Gastroenterol., 1968,50, 391–396.

  9. 9.

    KOSTIAINEN S., TEPPO L., VIRKKULA L. — Papilloma of the esophagus.Scand. J. Thorac. Cardiovasc. Surg., 1973,7, 95–97.

  10. 10.

    BENISCH B.M., MANTELL C. — Multiple squamous papillomas of the esophagus.Arch. Otolaryngol., 1974,100, 379.

  11. 11.

    HARRER W.V., SPRAGUE T.H., KEELEY F.X. — Squamous cell papilloma of the esophagus. A case report and literature review.J. Med. Soc. N.J., 1975,72, 229–232.

  12. 12.

    KADIAN R.S., MARSHALL H.E., JACOBS W.H. — The removal of an esophageal papilloma by endoscopic means. A case report and brief review of the literature.Am. J. Gastroenterol., 1975,64, 221–223.

  13. 13.

    DARANI M., VILLA F. — Multiple squamous papillomas of the esophagus diagnosed by endoscopy.J.A.M.A., 1976,236, 2655.

  14. 14.

    DOURDOUREKAS D., KAYMAKCALAN J., STEIGMANN F. — Squamous papilloma of the esophagus.Am. J. Gastroenterol., 1977,68, 379–380.

  15. 15.

    NUWAYHID N.S., BALLARD E.T., COTTON R. — Esophageal papillomatosis. Case report.Ann. Otol., 1977,86, 623–625.

  16. 16.

    WATERFALL W.E., SOMERS S., DESA D.J. — Benign oesophageal papillomatosis. A case report with review of the literature.J. Clin. Pathol., 1978,31, 111–115.

  17. 17.

    PARNELL S.A., PEPPERCORN M.S., ANTONIOLI D.A. et al. — Squamous celle papilloma of the esophagus. Report of a case after peptic esophagitis and repeated bougienage with review of the literature.Gastroenterology, 1978,74, 910–913.

  18. 18.

    FROOTKO N.J., ROGERS J.H. — Oesophageal papillomata in the child.J. Laryngol. Otol., 1978,92, 823–827.

  19. 19.

    RAVRY M.J. — Endoscopic resection of squamous papilloma of the esophagus.Am. J. Gastroenterol., 1979,71, 398–400.

  20. 20.

    LOMBARDI J.P., TANG D., MYHRE O.A. — Squamous cell papilloma of the esophagus: a case report and review of the literature.Int. Surg., 1980,65, 459–461.

  21. 21.

    SHAH A.N. — Endoscopic removal of squamous cell papilloma of the esophagus: a case report and review of the literature.Surg. Gastroenterol., 1984,3, 23–26.

  22. 22.

    ARIMA T., IKEDA K., SATOH T. et al. — Squamous cell papilloma of the esophagus in a child.Int. Surg., 1985,70, 177–178.

  23. 23.

    DE BORGES R.J., ACEVEDO F., MIRALLES E. et al. — Squamous papilloma of the esophagus diagnosed by cytology. Report of a case with concurrent occult epidermoid carcinoma.Acta Cytol., 1986,30, 487–490.

  24. 24.

    FAIVRE J., BORY R., MOULINIER B. — Benign tumors of the esophagus: value of endoscopy.Endoscopy, 1978,10, 264–268.

  25. 25.

    MILLER B.J., MURPHY F., LUKIE B.E. — Squamous cell papilloma of the esophagus.Can. J. Surg., 1978,21, 538–539.

  26. 26.

    ZEABART L.E., FABIAN J., NORD H.J. — Squamous papilloma of the esophagus. A report of three cases.Gastrointest. Endosc., 1979,25, 18–20.

  27. 27.

    STARR A.J., SHENOY B.V., RUFFOLO E.H. — Squamous papilloma of the esophagus.South Med. J., 1979,72, 1203–1205.

  28. 28.

    COLINA F., SOLIS J.A., MUNOZ M.T. — Squamous papilloma of the esophagus. A report of three cases and review of the literature.Am. J. Gastroenterol., 1980,74, 410–414.

  29. 29.

    JAVDAN P., PITMAN E.R. — Squamous papilloma of the esophagus.Dig. Dis. Sci., 1984,29, 317–320.

  30. 30.

    TOET A.E., DEKKER W., OP DEN ORTH J.O. et al. — Squamous cell papilloma of the esophagus: report of four cases.Gastrointest. Endosc., 1985,31, 77–79.

  31. 31.

    FERNANDEZ-RODRIGUEZ C.M., BADIA-FIGUE-ROLA N., RUIZ DEL ARBOL L. et al. — Squamous papilloma of the esophagus: report of six cases with longterm follow-up in four patients.Am. J. Gastroenterol., 1986,81, 1059–1062.

  32. 32.

    FRANZIN G., MUSOLA R., ZAMBONI G. et al. — Squamous papillomas of the esophagus.Gastrointest. Endosc., 1983,29, 104–106.

  33. 33.

    FRANZIN G., MUSOLA R., MANFRINI C. et al. — Squamous papilloma of the esophagus.Gastrointest. Endosc., 1984,30, 240.

  34. 34.

    MORINI S., BASSI O., PRIAMI R. et al. — Squamous cell papilloma of the esophagus: an overlooked lesion? Report of six endoscopic cases.Ital. J. Gastroenterol., 1984,16, 116–118.

  35. 35.

    BRINSON R.R., SCHUMAN B.M., MILLS L.R. et al. — Multiple squamous papillomas of the esophagus associated with Goltz Syndrome.Am. J. Gastroenterol., 1987,82, 1177–1179.

  36. 36.

    SABLICH R., BENEDETTI G., BIGNUCOLO S. et al. — Squamous cell papilloma of the esophagus. Report on 35 endoscopic cases.Endoscopy, 1988,20, 5–7.

  37. 37.

    PLACHTA A. — Benign tumors of the esophagus. Review of the literature and report of 99 cases.Am. J. Gastroenterol., 1962,38, 639–652.

  38. 38.

    ATTAH G.B., HAJDU S.I. — Benign and malignant tumors of the esophagus at autopsy.J. Thorac. Cardiovasc Surg., 1968,55, 396–404.

  39. 39.

    SYRJANEN K.J., PYRHONEN S., AUKEE S. et al. — Squamous celle papilloma of the oesophagus: a tumour probably caused by human papilloma virus (HPV).Diagn. Histopathol., 1982,5, 291–296.

  40. 40.

    SYRJANEN K.J. — Histological changes identical to those of condylomatous lesions found in esophageal squamous cell carcinomas.Arch. Geschwulstforsch, 1982,52, 283–292.

  41. 41.

    WINKLER B., CAPO V., REUMANN W. et al. — Human papillomavirus infection of the esophagus.Cancer, 1985,55, 149–155.

  42. 42.

    MONNIER Ph., SAVARY M., PASCHE R. — Contribution of Toluidine blue to bucco-pharyngo-oesophageal cancerology.Acta Endoscop., 1981,11, 299–315.

  43. 43.

    Galian A., LAVERGNE A. — Quelle est la signification pronostique des papillomes œsophagiens? DansLésions bénignes de l’œsophage el cancer (R. Giuli), Springer-Verlag, 1988, 17–21.

  44. 44.

    MONNIER Ph., SAVARY M., ANANI P. — Endoscopic morphology of « early » esophageal carcinoma. InEsophageal Disorders: Pathophysiology and Therapy (T.R. De Meester, D.B. Skinner), Raven Press, N.Y., 1985, 333–346.

  45. 45.

    DANOS O. — Papillomavirus, progrès récents.Path. Biol., 1986,34, 971–973.

  46. 46.

    HILLE J.J., MARKOWITZ S., MARGOLIUS K. et al. — Human papillomavirus and carcinoma of the oesophagus.N. Engl. J. Med., 1985,312, 1707.

  47. 47.

    KUKSKI J., DEMETER T., STERRETT G.F. et al. — Human papillomavirus DNA in oesophageal carcinoma.Lancet, 1986,11, 683–684.

  48. 48.

    LESEC G., GOGUSEV J., FERMAUD H. et al. — Présence d’un antigène viral du groupe « papilloma » dans un condylome œsophagien chez I’homme.Gastroentérol. Clin. Biol., 1985,9, 166–168.

  49. 49.

    OSTROW R.S., MANIAS DA., FONG W.J. et al. — A survey of human cancers for human papillomavirus DNA by filter hybridization.Cancer, 1987,59, 429–434.

  50. 50.

    KASHIMA H., MOUNTS P. — Tumors of the Head and Neck, Larynx, Lung and Esophagus and their possible relation to HPV. InPapillomaviruses and human disease (K. Syrjänen, L. Gissmann, L.E. Koss, Eds), Springer-Verlag, Berlin, 1987, 139–157.

  51. 51.

    Monnier Ph. —Le carcinome épidermoïde « précoce » de la voie digestive supérieure. Thèse de doctorat, Lausanne, 1986.

  52. 52.

    Tumor prevention, Treatment and Research Group, Chengchow, Honan, China: Pathology of early oesophageal squamous cell carcinoma.Chin. Med., 1977,3, 180–192.

Download references

Author information

Correspondence to Ph. Monnier or M. Savary or Ch. Fontolliet or J. Hürlimann or J. -B. Ollyo.

About this article

Cite this article

Monnier, P., Savary, M., Fontolliet, C. et al. Les papillomes de I’œsophage. Acta Endosc 19, 305 (1989). https://doi.org/10.1007/BF02966805

Download citation

Mots-clés

  • papillome
  • œsophage
  • endoscopic
  • papilloma virus humain
  • carcinome papillaire

Key words

  • papilloma
  • esophagus
  • endoscopy
  • human papillomavirus (HPV)
  • papillary carcinoma

Palabras-clave

  • Papiloma
  • esófago
  • endoscopéa
  • papilomavirus humano
  • carcinoma papilar