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Acta Endoscopica

, Volume 38, Issue 3, pp 229–241 | Cite as

Utilisation d’index de qualité pour la prise en charge du reflux gastro-œsophagien et l’évaluation des effets thérapeutiques

  • Fabio Pace
  • G. Bianchi Porro
Revue De La Littérature
  • 49 Downloads

Résumé

Le but de cette revue est de présenter les divers index utilisés dans l’évaluation de la qualité de vie liée à la santé (QVS) dans le cadre du reflux gastro-œsophagien (RGO); en passant en revue les différents instruments de mesure spécifiques disponibles, leur mise en application et leurs limites. Nous appréhenderons également l’effet du RGO sur la qualité de vie. Nous nous attacherons tout particulièrement à la non corrélation entre résultats endoscopiques et sévérité des symptômes, comme c’est le cas pour la pathologie liée au reflux non érosif maintenant reconnue comme une manifestation importante et hautement prévalente du RGO.

Les instruments de mesure de la qualité de vie sont utiles à l’évaluation de l’impact des divers traitements et interventions. L’altération de la qualité de vie fait maintenant partie de la définition la plus récente et la plus globale du RGO dont l’impact dépasse largement les seuls symptômes. Alors que les symptômes eux-mêmes ont un effet négatif sur la vie de ceux qui en souffrent, des effets secondaires contreproductifs apparaissent, dus à un fonctionnement physique, émotionnel et social altéré. Les troubles non gastro-intestinaux causés par la pathologie du RGO sont également responsables d’une altération de la qualité de vie. Il existe un besoin continuel de développer des instruments capables de mesurer avec précision l’impact du RGO et pouvant donner une interprétation utile au patient de même qu’au clinicien.

Mots-clés

œsophagite IPP qualité de vie liée à la santé reflux gastro-œsophagien symptômes 

Abbreviations

GERD

Gastroesophageal reflux disease

NERD

non-erosive reflux disease

HRQOL

health related quality of life

QOLRAD

Quality of life in reflux and dyspepsia

GSRS

Gastrointestinal symptoms rating scale

SF 36

Short Form 36 items

ProGERD

progression in GERD

PGWB

Psychological general well being

QALY

quality-adjusted life years

GERD-HRQL

Gastroesophageal reflux disease- health related quality of life

Abréviations

RGO

Reflux gastro-œsophagien

RGONE

RGO non érosif

QVS

Qualité de vie liée à la santé

QVRD

Qualité de vie dans reflux — dyspepsie

ESGI

Echelle symptomatique gastro-intestinale

SC 36 D

Schéma court de 36 données

PRGO

progression du RGO

BEPG

Bien-être psychologique général

QALY

Années de vie ajustées à la qualité

RGO-QVS

Reflux gastro-oesophagien — qualité de vie liée à la santé

The use of quality of life tools in the management of patients with gastroesophageal reflux disease

Summary

The purpose of this review is to present the various indices used for assessing health-related quality of life (HRQOL) in gastro-esophageal reflux disease (GERD), examining the range of generic and disease-specific instruments available, their applicability and limitations and to overview the effect of gastro-esophageal reflux disease on quality of life. We particularly focus on the issue of non-correlation between endoscopic findings and symptom severity, as witnessed by non-erosive reflux disease, which is now recognized as an important, highly prevalent, manifestation of GERD.

Quality-of-life instruments are useful in evaluating the impact of therapies and interventions. Impaired quality of life now forms part of the most recent, global definition of GERD, the impact of which goes beyond the symptoms alone. While the symptoms themselves have a negative effect on sufferers’ lives, there are secondary effects caused by impaired physical, emotional and social functioning on productivity. Non-gastrointestinal problems caused by GERD disease also impair quality of life. There is an ongoing need to develop instruments which truly measure the impact of gastro-esophageal reflux disease and which are readily interpretable to the individual patient and clinician.

Key-words

esophagitis GERD GERD symptoms health related quality of life (HRQOL) PPI 

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Copyright information

© Springer 2008

Authors and Affiliations

  • Fabio Pace
    • 1
  • G. Bianchi Porro
    • 1
  1. 1.Division and Chair of Gastroenterology, Department of Clinical SciencesUniversity Hospital « L. Sacco »MilanoItaly

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