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The action of tolbutamide on rat diaphragm

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Summary

PHYSIOLOGICAL concentrations of tolbutamide increased glucose uptake by the rat hemidiaphragm. The increase was not affected by excess insulin neutralising serum and although decreased by 0.006/M cysteine was still significantly greater than the basal uptake. These results suggest that the action of tolbutamide on glucose uptake is independent of insulin.

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Connon, J.J. The action of tolbutamide on rat diaphragm. I. J. Med. Sc. 2, 119 (1969). https://doi.org/10.1007/BF02958919

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