Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Toxic shock syndrome in a penicillin sensitive patient


While toxic shock syndrome (T.S.S.) has received considerable attention in the United States since its original description in 1978, it is not well documented as occurring in Ireland. The typical clinical features are described in this case whose management was complicated by penicillin hypersensitivity.

This is a preview of subscription content, log in to check access.


  1. 1.

    Todd, J., Fishaut, M., Kapral, F. and Welch, T. Toxic shock syndrome associated with phage group-1 staphylococci. Lancet 2: 1116–1118. 1978.

  2. 2.

    Reingold, A. L., Hargreth, W. T., Shands, K. al. Toxic shock syndrome surveillance in the United States 1980 to 1981. Ann. Intern. Med. 96: 875–880. 1982.

  3. 3.

    Chesney, P. J., Davis, J. P., Purdy, W. at. Clinical manifestations of toxic shock syndrome. J.A.M.A, 246: 741–748. 1981.

  4. 4.

    Rosene, K. A., Capass, M. R., Kastned, L. al. Persistent neuropsychological sequelae of toxic shock syndrome. Ann Intern. Med. 96: 865–870. 1985.

  5. 5.

    Reingold, A. L. Morbidity and Mortality Weekly Report 19: 33. 1985.

  6. 6.

    Gibney, R. T., Moore, A. and Muldowney, F. P. Toxic shock syndrome associated with post partum staphylococcal endometritis. Ir. Med. J. 76: 90–91. 1983.

  7. 7.

    Whitty, M., Fraser, S., Gemmell, C. G. and Wright, P. A. Toxic shock syndrome and endocarditis. Br. Med. J. 286: 1613. 1983.

  8. 8.

    Davis, J. P., Chesney, P. J., Wand, P. J. Toxic shock syndrome. N. Engl. J. Med. 303: 1429–1435. 1980.

  9. 9.

    Vergerant, J. M., Stolz, S. J., Crass, B. A., Nelson, D. B., Davis, J. P. Prevalance of serum antibody to staphylococcal enterotoxin F among Wisconsin residents; implications for toxic shock syndrome. J. Infect. Dis, 148: 692–698. 1983.

  10. 10.

    Staneck, J. L. and Bonventre, P. F. Toxic shock syndrome; a microbiological perspective. Surv. Syn. Pathol. Res. 3: 38–53. 1984.

  11. 11.

    Stallones, R. A. A reveiw of the epidemiologic studies of toxic shock syndrome. Ann Intern. Med. 96: 917–920. 1982.

  12. 12.

    Altemeirr, W. A., Lewis, S. A. and Schleivert, P. M. Staphylococcus aureus associated with toxic shock synrome. Ann. Intern. Med. 96: 978–982. 1982.

  13. 13.

    Washington, J. A. and Wilson, W. R. Erythromycin, a microbial and clinical perspective after 30 years of clinical use. Mayc Clin. Proc. 60: 184–203. 1985.

Download references

Author information

Correspondence to J. Feely.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Barry, M., Mathúna, P.M., de Azavedo, J.C.S. et al. Toxic shock syndrome in a penicillin sensitive patient. I.J.M.S. 156, 18 (1987).

Download citation


  • Erythromycin
  • Adult Respiratory Distress Syndrome
  • Cloxacillin
  • Toxic Shock Syndrome
  • Vaginal Discharge