Irish Journal of Medical Science

, Volume 160, Issue 9, pp 275–276 | Cite as

Multiple isolated brain metastases from a duke’s B colon carcinoma

  • Indra Sriram
  • M. A. Baumann


Brain metastases from colorectal carcinomas are very uncommon and are almost uniformly seen in the setting of advanced, systemic disease. We describe a unique case of multiple, isolated brain metastases occurring from a Duke’s B carcinoma of the sigmoid colon. Careful staging at two intervals at which clinical brain metastases were found did not disclose additional evidence of systemic disease. The cascade mechanism thought to be involved in the development of systemic metastases is reviewed, and a possible alternate route is suggested for direct access by tumor cells to the brain via Batson’s vertebral plexus.


Brain Metastasis Colorectal Carcinoma Cerebral Metastasis Careful Staging Multiple Brain Metastasis 
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Copyright information

© Springer 1991

Authors and Affiliations

  • Indra Sriram
    • 1
  • M. A. Baumann
    • 1
  1. 1.Department of MedicineVA Medical Center and Wright State University School of MedicineDaytonUSA

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