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Prognostic factors in childhood acute lymphoblastic leukaemia

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Summary

58 patients under the age of 14 years with acute lymphoblastic leukaemia were managed from 1971 to 1985. We analysed their overall survival from diagnosis to assess the prognostic significance of clinical and laboratory features presentatdiagnosis. Factors which were statistically significant included white blood count, platelet count, palpable lymph node enlargement, mediastinal widening on chest x-ray and palpable splenic enlargement The purpose of this study was to identify that subset of patients which might have benefitted from more intensive treatment.

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Correspondence to J. Armstrong or M. Pomeroy or J. J. Fennelly or S. Cahalane.

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Armstrong, J., Pomeroy, M., Fennelly, J.J. et al. Prognostic factors in childhood acute lymphoblastic leukaemia. I.J.M.S. 159, 40–43 (1990). https://doi.org/10.1007/BF02937246

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Keywords

  • Acute Lymphoblastic Leukaemia
  • White Cell Count
  • Acute Lymphoid Leukaemia
  • Acute Lymphocytic Leukaemia
  • Mediastinal Widening